PTPN3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_2000649Biological processregulation of sodium ion transmembrane transporter activity
GO_0006470Biological processprotein dephosphorylation
GO_0000165Biological processMAPK cascade
GO_0042059Biological processnegative regulation of epidermal growth factor receptor signaling pathway
GO_0051045Biological processnegative regulation of membrane protein ectodomain proteolysis
GO_0097421Biological processliver regeneration
GO_0045930Biological processnegative regulation of mitotic cell cycle
GO_0098902Biological processregulation of membrane depolarization during action potential
GO_0005856Cellular componentcytoskeleton
GO_0005886Cellular componentplasma membrane
GO_0009898Cellular componentcytoplasmic side of plasma membrane
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0051117Molecular functionATPase binding
GO_0017080Molecular functionsodium channel regulator activity
GO_0008092Molecular functioncytoskeletal protein binding
GO_0005515Molecular functionprotein binding
GO_0001784Molecular functionphosphotyrosine residue binding
GO_0004725Molecular functionprotein tyrosine phosphatase activity

IV. Literature review

[source]
Gene namePTPN3
Protein nameTyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1)
Tyrosine-protein phosphatase non-receptor type (EC 3.1.3.48)
SynonymsPTPH1
DescriptionFUNCTION: May act at junctions between the membrane and the cytoskeleton. Possesses tyrosine phosphatase activity.

FUNCTION: May act at junctions between the membrane and the cytoskeleton. .

FUNCTION: May act at junctions between the membrane and the cytoskeleton. .

AccessionsB7Z9V1
ENST00000446349.5 [P26045-3]
P26045
ENST00000262539.7
J3KN34
ENST00000374541.4 [P26045-1]
ENST00000412145.5 [P26045-2]