Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| astrocyte | 18 studies | 47% ± 20% | |
| oligodendrocyte | 15 studies | 39% ± 16% | |
| type II pneumocyte | 12 studies | 47% ± 22% | |
| basal cell | 11 studies | 39% ± 20% | |
| oligodendrocyte precursor cell | 11 studies | 30% ± 12% | |
| fibroblast | 10 studies | 35% ± 14% | |
| glutamatergic neuron | 9 studies | 31% ± 17% | |
| club cell | 9 studies | 35% ± 18% | |
| adipocyte | 9 studies | 34% ± 12% | |
| epithelial cell | 8 studies | 32% ± 22% | |
| endothelial cell | 8 studies | 34% ± 10% | |
| retinal rod cell | 8 studies | 60% ± 30% | |
| pericyte | 8 studies | 26% ± 9% | |
| ciliated cell | 7 studies | 23% ± 7% | |
| retinal cone cell | 7 studies | 68% ± 20% | |
| type I pneumocyte | 6 studies | 20% ± 3% | |
| GABAergic neuron | 6 studies | 32% ± 11% | |
| microglial cell | 6 studies | 39% ± 17% | |
| respiratory goblet cell | 5 studies | 33% ± 12% | |
| retinal pigment epithelial cell | 5 studies | 63% ± 18% | |
| mesothelial cell | 5 studies | 39% ± 22% | |
| smooth muscle cell | 5 studies | 30% ± 12% | |
| squamous epithelial cell | 4 studies | 38% ± 16% | |
| interneuron | 4 studies | 29% ± 9% | |
| connective tissue cell | 4 studies | 34% ± 10% | |
| kidney loop of Henle epithelial cell | 4 studies | 30% ± 12% | |
| renal principal cell | 4 studies | 52% ± 18% | |
| secretory cell | 3 studies | 30% ± 11% | |
| neuron | 3 studies | 24% ± 12% | |
| ependymal cell | 3 studies | 44% ± 17% | |
| Schwann cell | 3 studies | 34% ± 19% | |
| kidney distal convoluted tubule epithelial cell | 3 studies | 33% ± 13% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 100% | 4235.19 | 245 / 245 | 97% | 32.68 | 489 / 502 |
| thymus | 100% | 5837.99 | 651 / 653 | 95% | 34.69 | 577 / 605 |
| uterus | 100% | 5041.09 | 170 / 170 | 87% | 30.14 | 400 / 459 |
| kidney | 100% | 4828.29 | 89 / 89 | 87% | 18.13 | 781 / 901 |
| breast | 99% | 3278.22 | 453 / 459 | 85% | 21.57 | 947 / 1118 |
| brain | 84% | 2191.79 | 2217 / 2642 | 98% | 27.54 | 689 / 705 |
| bladder | 100% | 5117.00 | 21 / 21 | 79% | 25.23 | 400 / 504 |
| skin | 100% | 11422.11 | 1808 / 1809 | 79% | 17.43 | 372 / 472 |
| lung | 95% | 3818.43 | 547 / 578 | 80% | 26.47 | 919 / 1155 |
| esophagus | 93% | 4021.72 | 1345 / 1445 | 69% | 27.61 | 127 / 183 |
| adrenal gland | 91% | 1992.79 | 234 / 258 | 66% | 7.26 | 151 / 230 |
| ovary | 100% | 7715.45 | 180 / 180 | 44% | 6.61 | 191 / 430 |
| intestine | 71% | 1420.08 | 686 / 966 | 49% | 6.25 | 256 / 527 |
| pancreas | 37% | 498.50 | 121 / 328 | 78% | 11.03 | 139 / 178 |
| ureter | 0% | 0 | 0 / 0 | 100% | 8.44 | 1 / 1 |
| adipose | 100% | 3897.90 | 1199 / 1204 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 48.99 | 44 / 45 |
| blood vessel | 96% | 2609.22 | 1282 / 1335 | 0% | 0 | 0 / 0 |
| stomach | 59% | 1053.44 | 213 / 359 | 29% | 3.43 | 84 / 286 |
| heart | 48% | 944.74 | 416 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 41% | 5.31 | 33 / 80 |
| spleen | 39% | 585.27 | 93 / 241 | 0% | 0 | 0 / 0 |
| liver | 0% | 4.58 | 1 / 226 | 10% | 1.57 | 41 / 406 |
| lymph node | 0% | 0 | 0 / 0 | 10% | 1.33 | 3 / 29 |
| muscle | 1% | 12.34 | 8 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 7.60 | 4 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0051896 | Biological process | regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| GO_0006470 | Biological process | protein dephosphorylation |
| GO_0035335 | Biological process | peptidyl-tyrosine dephosphorylation |
| GO_0001933 | Biological process | negative regulation of protein phosphorylation |
| GO_0097237 | Biological process | cellular response to toxic substance |
| GO_1904890 | Biological process | negative regulation of excitatory synapse assembly |
| GO_0005856 | Cellular component | cytoskeleton |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005634 | Cellular component | nucleus |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0001650 | Cellular component | fibrillar center |
| GO_0005829 | Cellular component | cytosol |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0044297 | Cellular component | cell body |
| GO_0030027 | Cellular component | lamellipodium |
| GO_0036312 | Molecular function | phosphatidylinositol 3-kinase regulatory subunit binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0004725 | Molecular function | protein tyrosine phosphatase activity |
| Gene name | PTPN13 |
| Protein name | Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) (PTP-BAS) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (Protein-tyrosine phosphatase PTPL1) Uncharacterized protein PTPN13 Protein tyrosine phosphatase non-receptor type 13 |
| Synonyms | PTP1E PNP1 PTPL1 |
| Description | FUNCTION: Tyrosine phosphatase which negatively regulates FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling . May regulate phosphoinositide 3-kinase (PI3K) signaling through dephosphorylation of PIK3R2 . . |
| Accessions | ENST00000502971.5 Q4W5F5 D6R9M4 Q12923 ENST00000507902.5 ENST00000436978.5 [Q12923-4] ENST00000511467.1 [Q12923-4] D6R9X4 ENST00000427191.6 [Q12923-3] ENST00000316707.10 [Q12923-2] ENST00000411767.7 [Q12923-1] |