PTPN13 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0051896Biological processregulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
GO_0006470Biological processprotein dephosphorylation
GO_0035335Biological processpeptidyl-tyrosine dephosphorylation
GO_0001933Biological processnegative regulation of protein phosphorylation
GO_0097237Biological processcellular response to toxic substance
GO_1904890Biological processnegative regulation of excitatory synapse assembly
GO_0005856Cellular componentcytoskeleton
GO_0005886Cellular componentplasma membrane
GO_0070062Cellular componentextracellular exosome
GO_0005634Cellular componentnucleus
GO_0005654Cellular componentnucleoplasm
GO_0001650Cellular componentfibrillar center
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0044297Cellular componentcell body
GO_0030027Cellular componentlamellipodium
GO_0036312Molecular functionphosphatidylinositol 3-kinase regulatory subunit binding
GO_0005515Molecular functionprotein binding
GO_0004725Molecular functionprotein tyrosine phosphatase activity

IV. Literature review

[source]
Gene namePTPN13
Protein nameTyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) (PTP-BAS) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (Protein-tyrosine phosphatase PTPL1)
Uncharacterized protein PTPN13
Protein tyrosine phosphatase non-receptor type 13
SynonymsPTP1E
PNP1
PTPL1
DescriptionFUNCTION: Tyrosine phosphatase which negatively regulates FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling . May regulate phosphoinositide 3-kinase (PI3K) signaling through dephosphorylation of PIK3R2 . .

AccessionsENST00000502971.5
Q4W5F5
D6R9M4
Q12923
ENST00000507902.5
ENST00000436978.5 [Q12923-4]
ENST00000511467.1 [Q12923-4]
D6R9X4
ENST00000427191.6 [Q12923-3]
ENST00000316707.10 [Q12923-2]
ENST00000411767.7 [Q12923-1]