PTGFR | OmnibusX

Name	Number of supported studies	Average coverage
type II pneumocyte	5 studies	39% ± 8%	Explore
fibroblast	4 studies	22% ± 5%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of PTGFR at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	79%	512.74	203 / 258	73%	9.32	168 / 230
breast	94%	1474.24	432 / 459	43%	1.89	480 / 1118
bladder	95%	1797.00	20 / 21	33%	1.21	166 / 504
skin	97%	1998.98	1751 / 1809	27%	0.97	129 / 472
uterus	96%	1757.01	163 / 170	28%	2.58	128 / 459
kidney	67%	307.88	60 / 89	42%	2.53	380 / 901
prostate	48%	328.48	117 / 245	55%	3.39	274 / 502
intestine	62%	381.64	603 / 966	36%	0.98	192 / 527
lung	55%	273.88	319 / 578	38%	1.55	441 / 1155
adipose	87%	1502.14	1048 / 1204	0%	0	0 / 0
stomach	38%	278.89	138 / 359	48%	1.51	136 / 286
esophagus	55%	664.72	799 / 1445	31%	1.05	56 / 183
ovary	78%	465.09	141 / 180	7%	0.19	32 / 430
blood vessel	79%	932.31	1058 / 1335	0%	0	0 / 0
liver	21%	82.46	47 / 226	47%	5.93	191 / 406
pancreas	8%	30.93	27 / 328	60%	1.90	106 / 178
lymph node	0%	0	0 / 0	52%	1.18	15 / 29
muscle	37%	223.13	301 / 803	0%	0	0 / 0
brain	7%	40.42	195 / 2642	25%	1.06	178 / 705
thymus	28%	141.23	186 / 653	3%	0.04	16 / 605
heart	26%	124.68	225 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	18%	0.34	8 / 45
spleen	1%	6.68	3 / 241	0%	0	0 / 0
peripheral blood	1%	2.40	7 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0008284	Biological process	positive regulation of cell population proliferation
GO_0010628	Biological process	positive regulation of gene expression
GO_0032355	Biological process	response to estradiol
GO_0071799	Biological process	cellular response to prostaglandin D stimulus
GO_0007186	Biological process	G protein-coupled receptor signaling pathway
GO_0043066	Biological process	negative regulation of apoptotic process
GO_0006954	Biological process	inflammatory response
GO_0007204	Biological process	positive regulation of cytosolic calcium ion concentration
GO_0032496	Biological process	response to lipopolysaccharide
GO_0007567	Biological process	parturition
GO_0007189	Biological process	adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0005576	Cellular component	extracellular region
GO_0005886	Cellular component	plasma membrane
GO_0005737	Cellular component	cytoplasm
GO_0004958	Molecular function	prostaglandin F receptor activity

Gene name	PTGFR
Protein name	Prostaglandin F2-alpha receptor (PGF receptor) (PGF2-alpha receptor) (Prostanoid FP receptor) Prostanoid FP receptor Prostaglandin F2-alpha receptor (Prostanoid FP receptor)
Synonyms
Description	FUNCTION: Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum (By similarity). Isoforms 2 to 7 do not bind PGF2-alpha but are proposed to modulate signaling by participating in variant receptor complexes; heterodimers between isoform 1 and isoform 5 are proposed to be a receptor for prostamides including the synthetic analog bimatoprost. .
Accessions	ENST00000370757.8 [P43088-1] ENST00000370758.5 [P43088-1] ENST00000497923.5 F2Z2Z6 Q4LEK1 ENST00000370756.3 [P43088-2] Q71UN9 P43088

PTGFR report