PRXL2A | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	32 studies	32% ± 15%	Explore
endothelial cell of lymphatic vessel	19 studies	41% ± 17%	Explore
basal cell	14 studies	36% ± 15%	Explore
astrocyte	14 studies	36% ± 15%	Explore
pericyte	12 studies	30% ± 10%	Explore
epithelial cell	10 studies	43% ± 20%	Explore
vein endothelial cell	10 studies	32% ± 14%	Explore
plasmacytoid dendritic cell	10 studies	26% ± 10%	Explore
endothelial cell of vascular tree	10 studies	24% ± 5%	Explore
ciliated cell	9 studies	34% ± 20%	Explore
fibroblast	9 studies	26% ± 8%	Explore
smooth muscle cell	9 studies	22% ± 11%	Explore
adipocyte	9 studies	45% ± 13%	Explore
connective tissue cell	8 studies	28% ± 18%	Explore
neuron	8 studies	30% ± 16%	Explore
abnormal cell	7 studies	33% ± 6%	Explore
retinal cone cell	7 studies	55% ± 28%	Explore
glutamatergic neuron	7 studies	37% ± 17%	Explore
epithelial cell of proximal tubule	6 studies	28% ± 7%	Explore
oligodendrocyte precursor cell	6 studies	26% ± 7%	Explore
secretory cell	5 studies	29% ± 18%	Explore
kidney loop of Henle epithelial cell	5 studies	37% ± 4%	Explore
enterocyte	5 studies	25% ± 4%	Explore
enteroendocrine cell	5 studies	42% ± 12%	Explore
progenitor cell	4 studies	22% ± 4%	Explore
myofibroblast cell	4 studies	26% ± 2%	Explore
retinal ganglion cell	4 studies	69% ± 21%	Explore
capillary endothelial cell	4 studies	32% ± 10%	Explore
retinal pigment epithelial cell	4 studies	54% ± 20%	Explore
type II pneumocyte	4 studies	25% ± 15%	Explore
brush cell	4 studies	30% ± 7%	Explore
oligodendrocyte	4 studies	18% ± 3%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	34% ± 8%	Explore
endothelial cell of artery	3 studies	29% ± 8%	Explore
erythrocyte	3 studies	24% ± 8%	Explore
retina horizontal cell	3 studies	33% ± 12%	Explore
serous secreting cell	3 studies	20% ± 4%	Explore
Mueller cell	3 studies	27% ± 7%	Explore
GABAergic neuron	3 studies	39% ± 8%	Explore
keratinocyte	3 studies	30% ± 9%	Explore
interneuron	3 studies	30% ± 15%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	19% ± 2%	Explore
hepatocyte	3 studies	46% ± 32%	Explore
luminal cell of prostate epithelium	3 studies	19% ± 3%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	9 studies	26% ± 11%	Explore
kidney	5 studies	25% ± 4%	Explore
lung	5 studies	37% ± 15%	Explore
intestine	4 studies	24% ± 8%	Explore
eye	4 studies	24% ± 7%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	100%	6293.33	651 / 653	100%	55.18	605 / 605
liver	100%	5680.75	226 / 226	99%	75.29	403 / 406
prostate	100%	5664.90	244 / 245	99%	77.87	498 / 502
breast	100%	19623.45	459 / 459	98%	64.36	1101 / 1118
brain	99%	10251.58	2617 / 2642	98%	91.51	692 / 705
kidney	100%	5284.49	89 / 89	97%	55.24	875 / 901
bladder	100%	4497.43	21 / 21	96%	69.98	486 / 504
ovary	96%	2801.24	173 / 180	99%	41.10	427 / 430
intestine	99%	4732.02	958 / 966	92%	31.72	483 / 527
esophagus	93%	4109.53	1341 / 1445	96%	47.01	175 / 183
uterus	89%	2892.35	152 / 170	96%	62.34	442 / 459
pancreas	85%	1984.70	278 / 328	99%	40.33	176 / 178
skin	72%	4657.18	1304 / 1809	92%	48.20	432 / 472
lung	63%	1498.41	362 / 578	96%	46.59	1114 / 1155
adrenal gland	66%	1529.27	169 / 258	90%	50.04	207 / 230
stomach	66%	1720.69	237 / 359	83%	26.22	236 / 286
adipose	100%	23688.47	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	56.67	80 / 80
tonsil	0%	0	0 / 0	100%	64.08	45 / 45
ureter	0%	0	0 / 0	100%	93.16	1 / 1
heart	92%	4424.98	795 / 861	0%	0	0 / 0
muscle	92%	2651.43	738 / 803	0%	0	0 / 0
lymph node	0%	0	0 / 0	62%	11.29	18 / 29
blood vessel	60%	1938.19	800 / 1335	0%	0	0 / 0
spleen	24%	439.98	58 / 241	0%	0	0 / 0
peripheral blood	13%	270.75	119 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0098869	Biological process	cellular oxidant detoxification
GO_0045670	Biological process	regulation of osteoclast differentiation
GO_0005576	Cellular component	extracellular region
GO_0005737	Cellular component	cytoplasm
GO_0016209	Molecular function	antioxidant activity

IV. Literature review

[source]

Gene name	PRXL2A
Protein name	Peroxiredoxin-like 2A (Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes) (Protein PAMM) (Redox-regulatory protein FAM213A)
Synonyms	C10orf58 PSEC0139 PAMM UNQ611/PRO1198 PRO2290 FAM213A
Description	FUNCTION: Involved in redox regulation of the cell . Acts as an antioxidant . Inhibits TNFSF11-induced NFKB1 and JUN activation and osteoclast differentiation . May affect bone resorption and help to maintain bone mass . Acts as a negative regulator of macrophage-mediated inflammation by inhibiting macrophage production of inflammatory cytokines, probably through suppression of the MAPK signaling pathway . .
Accessions	ENST00000372187.9 [Q9BRX8-1] ENST00000372188.5 [Q9BRX8-1] ENST00000606162.6 [Q9BRX8-1] Q9BRX8 ENST00000372181.1 [Q9BRX8-1] ENST00000615554.4 [Q9BRX8-1] ENST00000372185.5 [Q9BRX8-2]

PRXL2A report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review