Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 26 studies | 27% ± 11% | |
fibroblast | 22 studies | 23% ± 6% | |
ciliated cell | 17 studies | 30% ± 13% | |
pericyte | 17 studies | 22% ± 6% | |
smooth muscle cell | 15 studies | 23% ± 6% | |
astrocyte | 13 studies | 33% ± 13% | |
endothelial cell of lymphatic vessel | 9 studies | 22% ± 3% | |
type I pneumocyte | 9 studies | 27% ± 6% | |
GABAergic neuron | 9 studies | 32% ± 20% | |
basal cell | 9 studies | 25% ± 7% | |
glutamatergic neuron | 8 studies | 36% ± 20% | |
epithelial cell | 8 studies | 37% ± 19% | |
macrophage | 7 studies | 21% ± 5% | |
type II pneumocyte | 7 studies | 24% ± 7% | |
oligodendrocyte | 7 studies | 25% ± 7% | |
endothelial cell of artery | 6 studies | 18% ± 2% | |
connective tissue cell | 6 studies | 18% ± 2% | |
adipocyte | 6 studies | 22% ± 5% | |
neuron | 6 studies | 33% ± 13% | |
oligodendrocyte precursor cell | 6 studies | 26% ± 7% | |
capillary endothelial cell | 5 studies | 17% ± 1% | |
myofibroblast cell | 5 studies | 25% ± 9% | |
club cell | 5 studies | 24% ± 7% | |
secretory cell | 5 studies | 20% ± 5% | |
interneuron | 5 studies | 39% ± 22% | |
pancreatic A cell | 4 studies | 37% ± 21% | |
cardiac muscle cell | 4 studies | 25% ± 3% | |
hepatocyte | 4 studies | 43% ± 28% | |
goblet cell | 4 studies | 31% ± 20% | |
endothelial cell of vascular tree | 4 studies | 23% ± 4% | |
type B pancreatic cell | 3 studies | 52% ± 23% | |
glomerular endothelial cell | 3 studies | 20% ± 4% | |
microglial cell | 3 studies | 22% ± 4% | |
vein endothelial cell | 3 studies | 18% ± 1% | |
luminal cell of prostate epithelium | 3 studies | 23% ± 4% | |
pancreatic ductal cell | 3 studies | 39% ± 22% | |
abnormal cell | 3 studies | 32% ± 10% | |
ependymal cell | 3 studies | 40% ± 16% | |
melanocyte | 3 studies | 19% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 11703.47 | 2642 / 2642 | 100% | 181.78 | 705 / 705 |
esophagus | 100% | 7092.57 | 1445 / 1445 | 100% | 61.24 | 183 / 183 |
ovary | 100% | 10306.70 | 180 / 180 | 100% | 59.28 | 430 / 430 |
intestine | 100% | 6360.62 | 966 / 966 | 100% | 53.76 | 526 / 527 |
lung | 100% | 8252.93 | 577 / 578 | 100% | 62.46 | 1154 / 1155 |
stomach | 100% | 5242.24 | 359 / 359 | 100% | 52.05 | 285 / 286 |
uterus | 100% | 8875.75 | 170 / 170 | 100% | 63.89 | 457 / 459 |
thymus | 100% | 9089.34 | 653 / 653 | 100% | 99.49 | 602 / 605 |
kidney | 100% | 7210.22 | 89 / 89 | 99% | 77.91 | 894 / 901 |
prostate | 100% | 5497.56 | 244 / 245 | 100% | 61.43 | 500 / 502 |
breast | 100% | 5915.75 | 459 / 459 | 99% | 63.18 | 1108 / 1118 |
bladder | 100% | 6256.90 | 21 / 21 | 98% | 47.62 | 495 / 504 |
skin | 100% | 5851.82 | 1808 / 1809 | 98% | 59.26 | 461 / 472 |
adrenal gland | 100% | 4862.72 | 258 / 258 | 97% | 57.30 | 222 / 230 |
pancreas | 96% | 2766.13 | 314 / 328 | 99% | 62.64 | 177 / 178 |
liver | 100% | 3373.30 | 226 / 226 | 90% | 32.93 | 366 / 406 |
adipose | 100% | 6310.36 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 8932.36 | 1335 / 1335 | 0% | 0 | 0 / 0 |
muscle | 100% | 5426.94 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 3431.04 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 61.86 | 45 / 45 |
heart | 98% | 5354.18 | 843 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 96% | 38.85 | 77 / 80 |
lymph node | 0% | 0 | 0 / 0 | 93% | 22.56 | 27 / 29 |
peripheral blood | 28% | 602.81 | 263 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0042542 | Biological process | response to hydrogen peroxide |
GO_0006470 | Biological process | protein dephosphorylation |
GO_0000278 | Biological process | mitotic cell cycle |
GO_0010629 | Biological process | negative regulation of gene expression |
GO_0034976 | Biological process | response to endoplasmic reticulum stress |
GO_0010288 | Biological process | response to lead ion |
GO_0035970 | Biological process | peptidyl-threonine dephosphorylation |
GO_1904528 | Biological process | positive regulation of microtubule binding |
GO_0032088 | Biological process | negative regulation of NF-kappaB transcription factor activity |
GO_0046580 | Biological process | negative regulation of Ras protein signal transduction |
GO_0008637 | Biological process | apoptotic mitochondrial changes |
GO_0070262 | Biological process | peptidyl-serine dephosphorylation |
GO_0046677 | Biological process | response to antibiotic |
GO_0010804 | Biological process | negative regulation of tumor necrosis factor-mediated signaling pathway |
GO_0043161 | Biological process | proteasome-mediated ubiquitin-dependent protein catabolic process |
GO_0000775 | Cellular component | chromosome, centromeric region |
GO_0000922 | Cellular component | spindle pole |
GO_0090443 | Cellular component | FAR/SIN/STRIPAK complex |
GO_0005829 | Cellular component | cytosol |
GO_0000159 | Cellular component | protein phosphatase type 2A complex |
GO_0005634 | Cellular component | nucleus |
GO_0017018 | Molecular function | myosin phosphatase activity |
GO_0046872 | Molecular function | metal ion binding |
GO_0044325 | Molecular function | transmembrane transporter binding |
GO_0048156 | Molecular function | tau protein binding |
GO_0004722 | Molecular function | protein serine/threonine phosphatase activity |
GO_0005515 | Molecular function | protein binding |
Gene name | PPP2CB |
Protein name | Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (PP2A-beta) (EC 3.1.3.16) Protein phosphatase 2 catalytic subunit beta protein-serine/threonine phosphatase (EC 3.1.3.16) Serine/threonine-protein phosphatase (EC 3.1.3.16) |
Synonyms | |
Description | FUNCTION: Catalytic subunit of protein phosphatase 2A (PP2A), a serine/threonine phosphatase involved in the regulation of a wide variety of enzymes, signal transduction pathways, and cellular events (Probable). PP2A can modulate the activity of phosphorylase B kinase, casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. . |
Accessions | ENST00000520056.1 E5RJX4 E5RHC1 P62714 ENST00000523023.1 ENST00000520334.5 H0YBN9 ENST00000221138.9 H0YC23 ENST00000518564.1 E5RFI3 ENST00000518243.5 |