Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| basal cell | 7 studies | 29% ± 18% | |
| type I pneumocyte | 7 studies | 21% ± 4% | |
| cardiac muscle cell | 5 studies | 28% ± 6% | |
| squamous epithelial cell | 3 studies | 40% ± 19% | |
| epithelial cell | 3 studies | 43% ± 19% |
Insufficient scRNA-seq data for expression of PPP1R13L at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 96% | 2227.99 | 555 / 578 | 97% | 37.93 | 1118 / 1155 |
| prostate | 93% | 3700.53 | 227 / 245 | 100% | 27.12 | 500 / 502 |
| thymus | 96% | 2167.47 | 629 / 653 | 94% | 27.61 | 569 / 605 |
| breast | 88% | 3571.81 | 406 / 459 | 99% | 35.84 | 1103 / 1118 |
| esophagus | 77% | 5502.45 | 1116 / 1445 | 99% | 86.33 | 182 / 183 |
| pancreas | 73% | 1334.38 | 239 / 328 | 97% | 51.73 | 172 / 178 |
| uterus | 68% | 1343.69 | 116 / 170 | 96% | 81.28 | 440 / 459 |
| kidney | 67% | 1347.46 | 60 / 89 | 89% | 27.45 | 799 / 901 |
| bladder | 57% | 1907.00 | 12 / 21 | 97% | 63.38 | 489 / 504 |
| intestine | 50% | 779.37 | 487 / 966 | 97% | 31.51 | 509 / 527 |
| ovary | 51% | 826.46 | 92 / 180 | 95% | 25.50 | 407 / 430 |
| stomach | 27% | 369.30 | 97 / 359 | 95% | 28.45 | 271 / 286 |
| adrenal gland | 87% | 1687.76 | 225 / 258 | 33% | 5.94 | 76 / 230 |
| skin | 86% | 14424.31 | 1559 / 1809 | 24% | 4.34 | 113 / 472 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 75.43 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 94.12 | 1 / 1 |
| blood vessel | 98% | 4350.90 | 1307 / 1335 | 0% | 0 | 0 / 0 |
| heart | 97% | 5973.27 | 835 / 861 | 0% | 0 | 0 / 0 |
| adipose | 84% | 1819.55 | 1014 / 1204 | 0% | 0 | 0 / 0 |
| liver | 12% | 182.34 | 26 / 226 | 49% | 12.21 | 200 / 406 |
| brain | 0% | 6.67 | 11 / 2642 | 40% | 5.75 | 285 / 705 |
| spleen | 16% | 272.49 | 39 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 5% | 87.13 | 48 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 5% | 0.49 | 4 / 80 |
| muscle | 1% | 20.65 | 12 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0009791 | Biological process | post-embryonic development |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0035264 | Biological process | multicellular organism growth |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_0048871 | Biological process | multicellular organismal-level homeostasis |
| GO_0060048 | Biological process | cardiac muscle contraction |
| GO_0042633 | Biological process | hair cycle |
| GO_0045597 | Biological process | positive regulation of cell differentiation |
| GO_0050728 | Biological process | negative regulation of inflammatory response |
| GO_0031076 | Biological process | embryonic camera-type eye development |
| GO_0003229 | Biological process | ventricular cardiac muscle tissue development |
| GO_0006915 | Biological process | apoptotic process |
| GO_0003215 | Biological process | cardiac right ventricle morphogenesis |
| GO_0005634 | Cellular component | nucleus |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0045171 | Cellular component | intercellular bridge |
| GO_0005829 | Cellular component | cytosol |
| GO_0030054 | Cellular component | cell junction |
| GO_0045296 | Molecular function | cadherin binding |
| GO_0003714 | Molecular function | transcription corepressor activity |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | PPP1R13L |
| Protein name | RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (NFkB-interacting protein 1) (PPP1R13B-like protein) Protein phosphatase 1 regulatory subunit 13 like IASPP short isoform (Protein phosphatase 1, regulatory (Inhibitor) subunit 13 like, isoform CRA_b) |
| Synonyms | RAI NKIP1 PPP1R13BL hCG_1776776 IASPP |
| Description | FUNCTION: Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis . . |
| Accessions | K7ENG6 K7EML6 ENST00000593226.5 K7EPP1 ENST00000589371.1 K7EN03 ENST00000591986.1 ENST00000418234.6 ENST00000360957.10 A7YME7 Q8WUF5 ENST00000592134.1 |
