POU2F3 | OmnibusX

Name	Number of supported studies	Average coverage
brush cell	4 studies	59% ± 20%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of POU2F3 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	96%	192.21	626 / 653	83%	5.48	503 / 605
breast	62%	186.00	283 / 459	90%	4.09	1004 / 1118
lung	74%	143.46	428 / 578	75%	4.20	871 / 1155
prostate	85%	155.09	208 / 245	38%	0.58	192 / 502
esophagus	45%	113.76	653 / 1445	67%	2.03	122 / 183
ovary	7%	4.91	12 / 180	94%	11.14	403 / 430
pancreas	16%	11.57	52 / 328	80%	4.62	142 / 178
bladder	38%	94.62	8 / 21	56%	3.24	280 / 504
intestine	47%	64.99	450 / 966	45%	1.21	238 / 527
skin	73%	5489.59	1316 / 1809	6%	0.40	29 / 472
stomach	31%	24.55	113 / 359	43%	1.50	122 / 286
uterus	11%	17.58	19 / 170	61%	3.57	278 / 459
tonsil	0%	0	0 / 0	47%	1.13	21 / 45
kidney	30%	27.36	27 / 89	6%	0.16	55 / 901
adrenal gland	13%	9.47	34 / 258	3%	0.04	6 / 230
adipose	14%	21.59	166 / 1204	0%	0	0 / 0
spleen	14%	12.68	33 / 241	0%	0	0 / 0
liver	5%	3.48	11 / 226	8%	0.21	33 / 406
peripheral blood	11%	29.92	102 / 929	0%	0	0 / 0
heart	5%	3.09	40 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	3%	0.11	1 / 29
blood vessel	2%	4.48	24 / 1335	0%	0	0 / 0
brain	0%	0.36	10 / 2642	1%	0.03	9 / 705
muscle	0%	1.67	4 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0030216	Biological process	keratinocyte differentiation
GO_0008544	Biological process	epidermis development
GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0043922	Biological process	negative regulation by host of viral transcription
GO_0042060	Biological process	wound healing
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0005730	Cellular component	nucleolus
GO_0005886	Cellular component	plasma membrane
GO_0005654	Cellular component	nucleoplasm
GO_0016604	Cellular component	nuclear body
GO_0005829	Cellular component	cytosol
GO_0000785	Cellular component	chromatin
GO_0005667	Cellular component	transcription regulator complex
GO_0005634	Cellular component	nucleus
GO_0000978	Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228	Molecular function	DNA-binding transcription activator activity, RNA polymerase II-specific
GO_0000981	Molecular function	DNA-binding transcription factor activity, RNA polymerase II-specific
GO_0043565	Molecular function	sequence-specific DNA binding
GO_1990837	Molecular function	sequence-specific double-stranded DNA binding
GO_0042802	Molecular function	identical protein binding
GO_0005515	Molecular function	protein binding

Gene name	POU2F3
Protein name	POU class 2 homeobox 3 POU domain, class 2, transcription factor 3 (Octamer-binding protein 11) (Oct-11) (Octamer-binding transcription factor 11) (OTF-11) (Transcription factor PLA-1) (Transcription factor Skn-1)
Synonyms	PLA1 OTF11
Description	FUNCTION: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and regulates cell type-specific differentiation pathways. Involved in the regulation of keratinocytes differentiation . The POU2F3-POU2AF2/POU2AF3 complex drives the expression of tuft-cell-specific genes, a rare chemosensory cells that coordinate immune and neural functions within mucosal epithelial tissues . .
Accessions	H0YLC5 ENST00000543440.7 [Q9UKI9-1] ENST00000533620.5 Q9UKI9 E9PIN6 ENST00000260264.8 [Q9UKI9-2] ENST00000532663.1

POU2F3 report