PLPP5 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006644Biological processphospholipid metabolic process
GO_0046839Biological processphospholipid dephosphorylation
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0005737Cellular componentcytoplasm
GO_0000810Molecular functiondiacylglycerol diphosphate phosphatase activity
GO_0008195Molecular functionphosphatidate phosphatase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene namePLPP5
Protein namePhospholipid phosphatase 5
Phospholipid phosphatase 5 (EC 3.1.3.4) (EC 3.6.1.75) (Phosphatidic acid phosphatase type 2 domain-containing protein 1B)
SynonymsPPAPDC1B
DPPL1
HTPAP
DescriptionFUNCTION: Magnesium-independent phospholipid phosphatase with broad substrate specificity . Preferentially catalyzes the conversion of diacylglycerol pyrophosphate into phosphatidate but can also act on phosphatidate and lysophosphatidate . Phospholipid phosphatases are involved in both the synthesis of lipids and the generation or degradation of lipid-signaling molecules . .

AccessionsENST00000419686.2 [Q8NEB5-4]
ENST00000531109.5
H0YDY2
ENST00000422581.6 [Q8NEB5-2]
H0YCQ3
ENST00000531823.5
ENST00000424479.7 [Q8NEB5-1]
E9PNB1
ENST00000524616.5
Q8NEB5
H0YCK0
ENST00000534339.5
ENST00000529359.5 [Q8NEB5-3]