PLEKHB2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
macrophage	28 studies	28% ± 7%	Explore
classical monocyte	20 studies	26% ± 9%	Explore
monocyte	16 studies	26% ± 8%	Explore
non-classical monocyte	16 studies	24% ± 10%	Explore
endothelial cell	15 studies	24% ± 6%	Explore
conventional dendritic cell	14 studies	25% ± 10%	Explore
myeloid cell	10 studies	28% ± 12%	Explore
dendritic cell	9 studies	29% ± 18%	Explore
ciliated cell	9 studies	26% ± 16%	Explore
alveolar macrophage	8 studies	25% ± 8%	Explore
plasmacytoid dendritic cell	7 studies	21% ± 6%	Explore
epithelial cell	7 studies	41% ± 17%	Explore
type I pneumocyte	6 studies	26% ± 4%	Explore
mononuclear phagocyte	6 studies	25% ± 6%	Explore
epithelial cell of proximal tubule	6 studies	19% ± 3%	Explore
kidney loop of Henle epithelial cell	6 studies	20% ± 3%	Explore
glutamatergic neuron	6 studies	41% ± 21%	Explore
renal alpha-intercalated cell	5 studies	43% ± 3%	Explore
CD16-positive, CD56-dim natural killer cell, human	5 studies	17% ± 1%	Explore
goblet cell	5 studies	22% ± 7%	Explore
natural killer cell	4 studies	20% ± 1%	Explore
pancreatic A cell	4 studies	42% ± 20%	Explore
retinal ganglion cell	4 studies	56% ± 25%	Explore
lymphocyte	4 studies	20% ± 7%	Explore
basal cell	4 studies	26% ± 6%	Explore
amacrine cell	4 studies	36% ± 18%	Explore
retina horizontal cell	4 studies	28% ± 12%	Explore
retinal cone cell	4 studies	40% ± 16%	Explore
retinal rod cell	4 studies	24% ± 6%	Explore
enterocyte	4 studies	19% ± 3%	Explore
leukocyte	4 studies	22% ± 4%	Explore
endothelial cell of vascular tree	4 studies	21% ± 4%	Explore
oligodendrocyte	4 studies	27% ± 8%	Explore
T cell	3 studies	16% ± 1%	Explore
mast cell	3 studies	23% ± 5%	Explore
ionocyte	3 studies	40% ± 5%	Explore
respiratory goblet cell	3 studies	22% ± 5%	Explore
squamous epithelial cell	3 studies	42% ± 21%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	18% ± 2%	Explore
hematopoietic precursor cell	3 studies	24% ± 1%	Explore
retinal bipolar neuron	3 studies	28% ± 6%	Explore
megakaryocyte	3 studies	21% ± 1%	Explore
tissue-resident macrophage	3 studies	24% ± 4%	Explore
abnormal cell	3 studies	24% ± 6%	Explore
intermediate monocyte	3 studies	39% ± 15%	Explore
CD8-positive, alpha-beta memory T cell	3 studies	16% ± 1%	Explore
gamma-delta T cell	3 studies	25% ± 8%	Explore
regulatory T cell	3 studies	18% ± 1%	Explore
GABAergic neuron	3 studies	52% ± 3%	Explore
pancreatic ductal cell	3 studies	51% ± 25%	Explore
neuron	3 studies	30% ± 10%	Explore
neutrophil	3 studies	20% ± 3%	Explore
enteroendocrine cell	3 studies	21% ± 5%	Explore
interneuron	3 studies	41% ± 19%	Explore
astrocyte	3 studies	31% ± 15%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	18% ± 3%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	8 studies	22% ± 10%	Explore
eye	6 studies	23% ± 8%	Explore
brain	6 studies	37% ± 13%	Explore
kidney	5 studies	18% ± 2%	Explore
pancreas	3 studies	44% ± 20%	Explore
peripheral blood	3 studies	27% ± 3%	Explore
intestine	3 studies	21% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	10762.61	2642 / 2642	100%	95.45	705 / 705
lung	100%	7742.85	578 / 578	100%	70.97	1155 / 1155
prostate	100%	5243.29	245 / 245	100%	87.00	502 / 502
stomach	100%	5793.31	359 / 359	100%	71.29	286 / 286
esophagus	100%	4056.51	1444 / 1445	100%	64.61	183 / 183
intestine	100%	5704.02	966 / 966	100%	76.27	525 / 527
breast	100%	4227.38	459 / 459	100%	74.91	1113 / 1118
kidney	100%	13434.85	89 / 89	99%	102.87	896 / 901
thymus	100%	5661.45	653 / 653	99%	76.71	600 / 605
skin	100%	5300.27	1808 / 1809	99%	93.70	468 / 472
ovary	99%	2274.88	179 / 180	100%	48.44	428 / 430
uterus	100%	2837.71	170 / 170	99%	47.37	454 / 459
bladder	100%	3737.48	21 / 21	97%	54.98	491 / 504
adrenal gland	100%	10643.49	258 / 258	95%	66.33	219 / 230
pancreas	96%	2355.43	314 / 328	98%	63.53	175 / 178
liver	92%	2319.03	207 / 226	51%	16.96	207 / 406
adipose	100%	4713.40	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	57.02	29 / 29
spleen	100%	7514.72	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	55.21	45 / 45
ureter	0%	0	0 / 0	100%	24.96	1 / 1
muscle	100%	4047.95	799 / 803	0%	0	0 / 0
blood vessel	99%	3611.54	1327 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	99%	58.13	79 / 80
peripheral blood	98%	5292.64	911 / 929	0%	0	0 / 0
heart	96%	3203.01	823 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0045595	Biological process	regulation of cell differentiation
GO_0055038	Cellular component	recycling endosome membrane
GO_0016020	Cellular component	membrane
GO_0005547	Molecular function	phosphatidylinositol-3,4,5-trisphosphate binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	PLEKHB2
Protein name	Pleckstrin homology domain-containing family B member 2 (PH domain-containing family B member 2) (Evectin-2) Pleckstrin homology domain containing B2
Synonyms	EVT2
Description	FUNCTION: Involved in retrograde transport of recycling endosomes. .
Accessions	ENST00000409158.5 [Q96CS7-6] ENST00000234115.10 [Q96CS7-3] ENST00000438882.6 [Q96CS7-5] A0A0A0MSI4 B7WPA5 A0A0A0MSE9 ENST00000439822.6 ENST00000628582.2 [Q96CS7-4] ENST00000693505.1 [Q96CS7-1] Q96CS7 ENST00000409612.5 [Q96CS7-1] ENST00000404460.5 ENST00000403716.5 ENST00000409279.1 [Q96CS7-1]

PLEKHB2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review