PLEKHA7 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0090136Biological processepithelial cell-cell adhesion
GO_0044331Biological processcell-cell adhesion mediated by cadherin
GO_0046931Biological processpore complex assembly
GO_0045218Biological processzonula adherens maintenance
GO_0005813Cellular componentcentrosome
GO_0030054Cellular componentcell junction
GO_0070062Cellular componentextracellular exosome
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005915Cellular componentzonula adherens
GO_0046930Cellular componentpore complex
GO_0070097Molecular functiondelta-catenin binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene namePLEKHA7
Protein nameHCG1992264, isoform CRA_a (PLEKHA7 protein)
Pleckstrin homology domain containing A7
Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7)
SynonymshCG_1992264
DescriptionFUNCTION: Required for zonula adherens biogenesis and maintenance . Acts via its interaction with CAMSAP3, which anchors microtubules at their minus-ends to zonula adherens, leading to the recruitment of KIFC3 kinesin to the junctional site . Mediates docking of ADAM10 to zonula adherens through a PDZD11-dependent interaction with the ADAM10-binding protein TSPAN33 . .

AccessionsE9PL74
ENST00000530489.5
ENST00000532079.1
A0A1B0GUM1
A0A1B0GUN0
ENST00000531066.6
ENST00000528376.5
ENST00000636113.1
Q6IQ23
Q8IUS9
A0A1B0GTN9
ENST00000355661.7 [Q6IQ23-1]
E9PKC0
ENST00000698836.1
ENST00000637162.1
ENST00000636090.1
A0A8Q3WLI9
H0YDE2
E9PIK1
ENST00000525581.2
A0A8V8TMS3
E9PN45
ENST00000696749.1