PLCB2 | OmnibusX

Name	Number of supported studies	Average coverage
classical monocyte	11 studies	27% ± 10%	Explore
non-classical monocyte	11 studies	28% ± 11%	Explore
conventional dendritic cell	8 studies	26% ± 14%	Explore
microglial cell	8 studies	22% ± 7%	Explore
dendritic cell	8 studies	27% ± 11%	Explore
macrophage	8 studies	23% ± 7%	Explore
monocyte	5 studies	25% ± 2%	Explore
myeloid cell	4 studies	22% ± 6%	Explore
brush cell	3 studies	24% ± 2%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of PLCB2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	100%	6234.22	578 / 578	96%	11.00	1105 / 1155
intestine	95%	2189.07	919 / 966	86%	5.99	453 / 527
breast	85%	1198.39	389 / 459	95%	7.47	1060 / 1118
brain	74%	1234.39	1968 / 2642	99%	14.95	696 / 705
stomach	81%	880.73	290 / 359	90%	5.95	258 / 286
prostate	91%	1398.94	223 / 245	79%	3.48	397 / 502
uterus	80%	811.08	136 / 170	90%	6.06	413 / 459
thymus	83%	1134.39	542 / 653	84%	9.69	506 / 605
bladder	86%	1569.43	18 / 21	76%	6.04	382 / 504
kidney	69%	1024.54	61 / 89	91%	10.01	817 / 901
adrenal gland	95%	1510.66	245 / 258	57%	2.67	132 / 230
esophagus	78%	795.88	1125 / 1445	74%	4.08	136 / 183
liver	76%	853.31	172 / 226	57%	3.07	232 / 406
pancreas	30%	305.88	97 / 328	93%	12.44	166 / 178
skin	27%	222.92	489 / 1809	92%	13.54	436 / 472
ovary	38%	330.38	69 / 180	80%	5.41	344 / 430
lymph node	0%	0	0 / 0	100%	25.90	29 / 29
spleen	100%	18356.89	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	2.30	1 / 1
peripheral blood	99%	13651.28	924 / 929	0%	0	0 / 0
adipose	96%	2113.33	1152 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	88%	11.69	70 / 80
tonsil	0%	0	0 / 0	87%	7.29	39 / 45
heart	72%	864.26	623 / 861	0%	0	0 / 0
blood vessel	69%	1050.10	927 / 1335	0%	0	0 / 0
muscle	9%	65.10	74 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0006644	Biological process	phospholipid metabolic process
GO_0007186	Biological process	G protein-coupled receptor signaling pathway
GO_0001580	Biological process	detection of chemical stimulus involved in sensory perception of bitter taste
GO_0046488	Biological process	phosphatidylinositol metabolic process
GO_0007200	Biological process	phospholipase C-activating G protein-coupled receptor signaling pathway
GO_0051209	Biological process	release of sequestered calcium ion into cytosol
GO_0048015	Biological process	phosphatidylinositol-mediated signaling
GO_0016042	Biological process	lipid catabolic process
GO_0098992	Cellular component	neuronal dense core vesicle
GO_0005829	Cellular component	cytosol
GO_0031680	Cellular component	G-protein beta/gamma-subunit complex
GO_0005737	Cellular component	cytoplasm
GO_0004629	Molecular function	phospholipase C activity
GO_0031683	Molecular function	G-protein beta/gamma-subunit complex binding
GO_0005509	Molecular function	calcium ion binding
GO_0005515	Molecular function	protein binding
GO_0005543	Molecular function	phospholipid binding
GO_0004435	Molecular function	phosphatidylinositol phospholipase C activity

Gene name	PLCB2
Protein name	Phospholipase C beta 2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-2) (Phospholipase C-beta-2) (PLC-beta-2) PLCB2 protein (Phospholipase C beta 2) (Phospholipase C, beta 2)
Synonyms	hCG_38956
Description	FUNCTION: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. .
Accessions	ENST00000456256.6 [Q00722-3] ENST00000559671.5 H0YKR9 Q00722 Q9BVT6 ENST00000543785.3 ENST00000559618.1 ENST00000557821.5 [Q00722-2] ENST00000260402.8 [Q00722-1] H0YNI4

PLCB2 report