Name | Number of supported studies | Average coverage | |
---|---|---|---|
natural killer cell | 7 studies | 19% ± 3% | |
CD16-positive, CD56-dim natural killer cell, human | 6 studies | 17% ± 2% | |
epithelial cell | 6 studies | 31% ± 13% | |
endothelial cell | 5 studies | 24% ± 5% | |
CD16-negative, CD56-bright natural killer cell, human | 4 studies | 18% ± 3% | |
CD4-positive, alpha-beta T cell | 4 studies | 18% ± 2% | |
B cell | 4 studies | 16% ± 2% | |
fibroblast | 4 studies | 24% ± 5% | |
ciliated cell | 4 studies | 28% ± 5% | |
CD8-positive, alpha-beta T cell | 4 studies | 19% ± 3% | |
naive B cell | 3 studies | 16% ± 1% | |
pericyte | 3 studies | 17% ± 1% | |
amacrine cell | 3 studies | 34% ± 9% | |
abnormal cell | 3 studies | 24% ± 6% | |
CD8-positive, alpha-beta memory T cell | 3 studies | 18% ± 3% | |
GABAergic neuron | 3 studies | 29% ± 3% | |
glutamatergic neuron | 3 studies | 38% ± 7% | |
dendritic cell | 3 studies | 25% ± 7% | |
gamma-delta T cell | 3 studies | 27% ± 16% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 2214.73 | 2642 / 2642 | 100% | 55.90 | 705 / 705 |
esophagus | 100% | 1586.62 | 1445 / 1445 | 100% | 21.86 | 183 / 183 |
liver | 100% | 966.71 | 226 / 226 | 100% | 25.32 | 406 / 406 |
prostate | 100% | 1471.80 | 245 / 245 | 100% | 35.52 | 502 / 502 |
breast | 100% | 1701.97 | 459 / 459 | 100% | 45.06 | 1117 / 1118 |
uterus | 100% | 1762.28 | 170 / 170 | 100% | 32.03 | 458 / 459 |
ovary | 100% | 1679.79 | 180 / 180 | 100% | 19.84 | 428 / 430 |
thymus | 100% | 1292.69 | 652 / 653 | 100% | 33.19 | 603 / 605 |
bladder | 100% | 1635.48 | 21 / 21 | 99% | 26.55 | 501 / 504 |
intestine | 100% | 1637.91 | 966 / 966 | 99% | 24.97 | 523 / 527 |
adrenal gland | 100% | 1878.95 | 258 / 258 | 99% | 36.30 | 228 / 230 |
kidney | 100% | 1155.45 | 89 / 89 | 99% | 32.47 | 891 / 901 |
stomach | 99% | 1130.62 | 357 / 359 | 99% | 22.26 | 283 / 286 |
lung | 96% | 1114.24 | 556 / 578 | 100% | 25.45 | 1154 / 1155 |
skin | 100% | 2287.98 | 1809 / 1809 | 95% | 31.85 | 450 / 472 |
pancreas | 96% | 622.15 | 314 / 328 | 99% | 27.53 | 177 / 178 |
adipose | 100% | 1723.46 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 1852.76 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 42.53 | 29 / 29 |
spleen | 100% | 1222.02 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 32.24 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 11.29 | 1 / 1 |
muscle | 100% | 1394.83 | 802 / 803 | 0% | 0 | 0 / 0 |
heart | 97% | 985.56 | 832 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 78% | 13.04 | 62 / 80 |
peripheral blood | 64% | 815.46 | 597 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0043489 | Biological process | RNA stabilization |
GO_0015031 | Biological process | protein transport |
GO_0006408 | Biological process | snRNA export from nucleus |
GO_0015030 | Cellular component | Cajal body |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_1990904 | Cellular component | ribonucleoprotein complex |
GO_0043025 | Cellular component | neuronal cell body |
GO_0005634 | Cellular component | nucleus |
GO_0140262 | Molecular function | mRNA cap binding complex binding |
GO_0015643 | Molecular function | toxic substance binding |
GO_0005515 | Molecular function | protein binding |
GO_0003723 | Molecular function | RNA binding |
Gene name | PHAX |
Protein name | Phosphorylated adapter RNA export protein (RNA U small nuclear RNA export adapter protein) |
Synonyms | RNUXA |
Description | FUNCTION: A phosphoprotein adapter involved in the XPO1-mediated U snRNA export from the nucleus. Bridge components required for U snRNA export, the cap binding complex (CBC)-bound snRNA on the one hand and the GTPase Ran in its active GTP-bound form together with the export receptor XPO1 on the other. Its phosphorylation in the nucleus is required for U snRNA export complex assembly and export, while its dephosphorylation in the cytoplasm causes export complex disassembly. It is recycled back to the nucleus via the importin alpha/beta heterodimeric import receptor. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Its compartmentalized phosphorylation cycle may also contribute to the directionality of export. Binds strongly to m7G-capped U1 and U5 small nuclear RNAs (snRNAs) in a sequence-unspecific manner and phosphorylation-independent manner (By similarity). Also plays a role in the biogenesis of U3 small nucleolar RNA (snoRNA). Involved in the U3 snoRNA transport from nucleoplasm to Cajal bodies. Binds strongly to m7G-capped U3, U8 and U13 precursor snoRNAs and weakly to trimethylated (TMG)-capped U3, U8 and U13 snoRNAs. Binds also to telomerase RNA. . |
Accessions | Q9H814 ENST00000297540.5 |