Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 17 studies | 35% ± 15% | |
astrocyte | 15 studies | 51% ± 19% | |
oligodendrocyte precursor cell | 14 studies | 47% ± 17% | |
pericyte | 11 studies | 47% ± 21% | |
mast cell | 9 studies | 39% ± 13% | |
endothelial cell of lymphatic vessel | 8 studies | 55% ± 12% | |
glutamatergic neuron | 7 studies | 39% ± 19% | |
fibroblast | 7 studies | 31% ± 12% | |
GABAergic neuron | 6 studies | 39% ± 13% | |
mesothelial cell | 6 studies | 41% ± 12% | |
cardiac muscle cell | 5 studies | 20% ± 4% | |
hepatocyte | 4 studies | 47% ± 27% | |
vein endothelial cell | 4 studies | 29% ± 8% | |
macrophage | 4 studies | 22% ± 3% | |
adipocyte | 4 studies | 26% ± 11% | |
interneuron | 4 studies | 41% ± 28% | |
smooth muscle cell | 3 studies | 44% ± 18% | |
endocardial cell | 3 studies | 45% ± 20% | |
GABAergic amacrine cell | 3 studies | 31% ± 2% | |
Mueller cell | 3 studies | 33% ± 10% | |
glycinergic amacrine cell | 3 studies | 20% ± 3% | |
endothelial cell of vascular tree | 3 studies | 21% ± 4% | |
connective tissue cell | 3 studies | 34% ± 24% | |
ependymal cell | 3 studies | 33% ± 14% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
kidney | 100% | 931.20 | 89 / 89 | 93% | 6.22 | 839 / 901 |
thymus | 100% | 990.83 | 652 / 653 | 91% | 7.24 | 549 / 605 |
adrenal gland | 98% | 452.15 | 254 / 258 | 92% | 5.10 | 211 / 230 |
brain | 90% | 1365.54 | 2384 / 2642 | 98% | 6.12 | 690 / 705 |
prostate | 100% | 880.70 | 244 / 245 | 87% | 2.59 | 437 / 502 |
breast | 98% | 568.16 | 452 / 459 | 71% | 1.83 | 796 / 1118 |
ovary | 100% | 2267.69 | 180 / 180 | 56% | 1.35 | 241 / 430 |
bladder | 100% | 1195.71 | 21 / 21 | 55% | 2.15 | 278 / 504 |
uterus | 99% | 1315.18 | 168 / 170 | 50% | 3.53 | 231 / 459 |
esophagus | 78% | 405.56 | 1130 / 1445 | 60% | 1.44 | 110 / 183 |
lung | 74% | 243.84 | 427 / 578 | 57% | 1.77 | 657 / 1155 |
intestine | 99% | 512.76 | 954 / 966 | 28% | 0.70 | 147 / 527 |
stomach | 83% | 691.83 | 297 / 359 | 40% | 1.98 | 115 / 286 |
liver | 78% | 245.08 | 177 / 226 | 38% | 1.04 | 156 / 406 |
skin | 55% | 498.57 | 1002 / 1809 | 57% | 4.05 | 268 / 472 |
ureter | 0% | 0 | 0 / 0 | 100% | 3.42 | 1 / 1 |
heart | 100% | 709.99 | 858 / 861 | 0% | 0 | 0 / 0 |
adipose | 100% | 939.18 | 1198 / 1204 | 0% | 0 | 0 / 0 |
pancreas | 16% | 35.96 | 52 / 328 | 76% | 2.33 | 135 / 178 |
muscle | 92% | 323.18 | 735 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 73% | 330.62 | 973 / 1335 | 0% | 0 | 0 / 0 |
spleen | 49% | 124.78 | 119 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 47% | 0.66 | 21 / 45 |
lymph node | 0% | 0 | 0 / 0 | 28% | 0.53 | 8 / 29 |
eye | 0% | 0 | 0 / 0 | 16% | 0.45 | 13 / 80 |
peripheral blood | 0% | 0.17 | 1 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007165 | Biological process | signal transduction |
GO_0019933 | Biological process | cAMP-mediated signaling |
GO_0006198 | Biological process | cAMP catabolic process |
GO_0007268 | Biological process | chemical synaptic transmission |
GO_0005829 | Cellular component | cytosol |
GO_0045202 | Cellular component | synapse |
GO_0048471 | Cellular component | perinuclear region of cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0047555 | Molecular function | 3',5'-cyclic-GMP phosphodiesterase activity |
GO_0004115 | Molecular function | 3',5'-cyclic-AMP phosphodiesterase activity |
GO_0046872 | Molecular function | metal ion binding |
Gene name | PDE7B |
Protein name | Phosphodiesterase 7B Phosphodiesterase (EC 3.1.4.-) 3',5'-cyclic-AMP phosphodiesterase 7B (EC 3.1.4.53) (cAMP-specific phosphodiesterase 7B) PDE7B protein |
Synonyms | protein variant |
Description | FUNCTION: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes . May be involved in the control of cAMP-mediated neural activity and cAMP metabolism in the brain . . |
Accessions | Q9NP56 A1E5M1 ENST00000446774.1 Q6NSC8 ENST00000615259.4 ENST00000308191.11 H0Y689 Q4LE81 |