PDE7B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0019933Biological processcAMP-mediated signaling
GO_0006198Biological processcAMP catabolic process
GO_0007268Biological processchemical synaptic transmission
GO_0005829Cellular componentcytosol
GO_0045202Cellular componentsynapse
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0005634Cellular componentnucleus
GO_0047555Molecular function3',5'-cyclic-GMP phosphodiesterase activity
GO_0004115Molecular function3',5'-cyclic-AMP phosphodiesterase activity
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene namePDE7B
Protein namePhosphodiesterase 7B
Phosphodiesterase (EC 3.1.4.-)
3',5'-cyclic-AMP phosphodiesterase 7B (EC 3.1.4.53) (cAMP-specific phosphodiesterase 7B)
PDE7B protein
Synonymsprotein
variant
DescriptionFUNCTION: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes . May be involved in the control of cAMP-mediated neural activity and cAMP metabolism in the brain . .

AccessionsQ9NP56
A1E5M1
ENST00000446774.1
Q6NSC8
ENST00000615259.4
ENST00000308191.11
H0Y689
Q4LE81