P2RY2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of P2RY2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of P2RY2 at tissue level.

III. Associated gene sets

GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0007200Biological processphospholipase C-activating G protein-coupled receptor signaling pathway
GO_0035589Biological processG protein-coupled purinergic nucleotide receptor signaling pathway
GO_0006873Biological processintracellular monoatomic ion homeostasis
GO_0097746Biological processblood vessel diameter maintenance
GO_0070257Biological processpositive regulation of mucus secretion
GO_0071318Biological processcellular response to ATP
GO_0005886Cellular componentplasma membrane
GO_0045030Molecular functionG protein-coupled UTP receptor activity
GO_0038023Molecular functionsignaling receptor activity
GO_0005515Molecular functionprotein binding
GO_0031686Molecular functionA1 adenosine receptor binding
GO_0045028Molecular functionG protein-coupled purinergic nucleotide receptor activity

IV. Literature review

[source]
Gene nameP2RY2
Protein nameP2Y purinoceptor 2 (P2Y2) (ATP receptor) (P2U purinoceptor 1) (P2U1) (P2U receptor 1) (Purinergic receptor)
P2Y purinoceptor 2
SynonymsP2RU1
DescriptionFUNCTION: Receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. The affinity range is UTP = ATP > ATP-gamma-S >> 2-methylthio-ATP = ADP.

AccessionsENST00000393596.2
ENST00000311131.6
P41231
ENST00000393597.7
C6G7W2
C6G7W1