OTP report

I. Expression across cell types

Insufficient scRNA-seq data for expression of OTP at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of OTP at tissue level.

III. Associated gene sets

GO_0002052Biological processpositive regulation of neuroblast proliferation
GO_0030182Biological processneuron differentiation
GO_0021985Biological processneurohypophysis development
GO_0061101Biological processneuroendocrine cell differentiation
GO_0007405Biological processneuroblast proliferation
GO_0021979Biological processhypothalamus cell differentiation
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0071542Biological processdopaminergic neuron differentiation
GO_0021879Biological processforebrain neuron differentiation
GO_0016604Cellular componentnuclear body
GO_0005654Cellular componentnucleoplasm
GO_0000785Cellular componentchromatin
GO_0001650Cellular componentfibrillar center
GO_0003677Molecular functionDNA binding
GO_0000977Molecular functionRNA polymerase II transcription regulatory region sequence-specific DNA binding
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0001227Molecular functionDNA-binding transcription repressor activity, RNA polymerase II-specific

IV. Literature review

[source]
Gene nameOTP
Protein nameHomeobox protein orthopedia
Synonyms
DescriptionFUNCTION: Probably involved in the differentiation of hypothalamic neuroendocrine cells.

AccessionsQ5XKR4
ENST00000306422.5