OLIG2 | OmnibusX

Name	Number of supported studies	Average coverage
oligodendrocyte precursor cell	11 studies	44% ± 17%	Explore
oligodendrocyte	5 studies	19% ± 2%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of OLIG2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	99%	2962.58	2628 / 2642	98%	359.84	688 / 705
skin	0%	0	0 / 1809	11%	3.77	53 / 472
peripheral blood	2%	7.84	17 / 929	0%	0	0 / 0
kidney	0%	0	0 / 89	1%	0.40	13 / 901
thymus	0%	0	0 / 653	0%	0.19	2 / 605
heart	0%	0.38	1 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
adipose	0%	0	0 / 1204	0%	0	0 / 0
adrenal gland	0%	0	0 / 258	0%	0	0 / 230
bladder	0%	0	0 / 21	0%	0	0 / 504
blood vessel	0%	0	0 / 1335	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
breast	0%	0	0 / 459	0%	0	0 / 1118
diaphragm	0%	0	0 / 0	0%	0	0 / 0
esophagus	0%	0	0 / 1445	0%	0	0 / 183
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
intestine	0%	0	0 / 966	0%	0	0 / 527
liver	0%	0	0 / 226	0%	0	0 / 406
lung	0%	0	0 / 578	0%	0	0 / 1155
lymph node	0%	0	0 / 0	0%	0	0 / 29
muscle	0%	0	0 / 803	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
ovary	0%	0	0 / 180	0%	0	0 / 430
pancreas	0%	0	0 / 328	0%	0	0 / 178
placenta	0%	0	0 / 0	0%	0	0 / 0
prostate	0%	0	0 / 245	0%	0	0 / 502
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0
stomach	0%	0	0 / 359	0%	0	0 / 286
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1
uterus	0%	0	0 / 170	0%	0	0 / 459

GO_0021794	Biological process	thalamus development
GO_0061564	Biological process	axon development
GO_0042552	Biological process	myelination
GO_0048663	Biological process	neuron fate commitment
GO_0021530	Biological process	spinal cord oligodendrocyte cell fate specification
GO_0000122	Biological process	negative regulation of transcription by RNA polymerase II
GO_0045665	Biological process	negative regulation of neuron differentiation
GO_0048714	Biological process	positive regulation of oligodendrocyte differentiation
GO_0021522	Biological process	spinal cord motor neuron differentiation
GO_0007423	Biological process	sensory organ development
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0005737	Cellular component	cytoplasm
GO_0000785	Cellular component	chromatin
GO_0005634	Cellular component	nucleus
GO_0000981	Molecular function	DNA-binding transcription factor activity, RNA polymerase II-specific
GO_1990837	Molecular function	sequence-specific double-stranded DNA binding
GO_0042802	Molecular function	identical protein binding
GO_0070888	Molecular function	E-box binding
GO_0046983	Molecular function	protein dimerization activity
GO_0005515	Molecular function	protein binding
GO_0071837	Molecular function	HMG box domain binding

Gene name	OLIG2
Protein name	Oligodendrocyte transcription factor 2 Oligodendrocyte transcription factor 2 (Oligo2) (Class B basic helix-loop-helix protein 1) (bHLHb1) (Class E basic helix-loop-helix protein 19) (bHLHe19) (Protein kinase C-binding protein 2) (Protein kinase C-binding protein RACK17)
Synonyms	RACK17 BHLHB1 BHLHE19 PRKCBP2
Description	FUNCTION: Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Functions together with ZNF488 to promote oligodendrocyte differentiation. Cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube. Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development. .
Accessions	C9J444 ENST00000382357.4 ENST00000430860.1 ENST00000333337.3 Q13516

OLIG2 report