Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 7 studies | 26% ± 8% | |
| oligodendrocyte | 6 studies | 25% ± 6% | |
| microglial cell | 5 studies | 21% ± 4% | |
| adipocyte | 5 studies | 18% ± 3% | |
| astrocyte | 5 studies | 29% ± 8% | |
| macrophage | 5 studies | 20% ± 3% | |
| epithelial cell | 4 studies | 22% ± 6% | |
| GABAergic neuron | 4 studies | 40% ± 14% | |
| glutamatergic neuron | 4 studies | 48% ± 15% | |
| oligodendrocyte precursor cell | 4 studies | 26% ± 7% | |
| endothelial cell of lymphatic vessel | 4 studies | 19% ± 2% | |
| type II pneumocyte | 3 studies | 19% ± 4% | |
| transit amplifying cell | 3 studies | 29% ± 17% | |
| interneuron | 3 studies | 42% ± 20% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 6 studies | 35% ± 13% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 100% | 1052.67 | 459 / 459 | 100% | 35.87 | 1118 / 1118 |
| esophagus | 100% | 912.89 | 1445 / 1445 | 100% | 15.61 | 183 / 183 |
| ovary | 100% | 1278.85 | 180 / 180 | 100% | 14.16 | 430 / 430 |
| intestine | 100% | 1178.20 | 966 / 966 | 100% | 12.36 | 526 / 527 |
| prostate | 100% | 1276.18 | 245 / 245 | 100% | 19.84 | 501 / 502 |
| lung | 100% | 957.37 | 576 / 578 | 100% | 17.16 | 1155 / 1155 |
| stomach | 100% | 768.84 | 359 / 359 | 100% | 12.43 | 285 / 286 |
| brain | 100% | 836.52 | 2631 / 2642 | 100% | 14.64 | 705 / 705 |
| uterus | 100% | 1262.61 | 170 / 170 | 99% | 18.08 | 455 / 459 |
| thymus | 100% | 1197.01 | 653 / 653 | 99% | 14.58 | 598 / 605 |
| bladder | 100% | 1171.67 | 21 / 21 | 99% | 14.63 | 498 / 504 |
| pancreas | 100% | 672.48 | 327 / 328 | 99% | 10.42 | 176 / 178 |
| skin | 100% | 1578.14 | 1809 / 1809 | 98% | 17.32 | 463 / 472 |
| kidney | 100% | 855.06 | 89 / 89 | 96% | 9.28 | 862 / 901 |
| adrenal gland | 100% | 981.45 | 258 / 258 | 91% | 8.33 | 209 / 230 |
| liver | 100% | 440.97 | 226 / 226 | 87% | 7.49 | 354 / 406 |
| adipose | 100% | 924.96 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 13.97 | 29 / 29 |
| spleen | 100% | 1383.66 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 15.81 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 9.46 | 1 / 1 |
| blood vessel | 100% | 934.29 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 98% | 437.41 | 789 / 803 | 0% | 0 | 0 / 0 |
| heart | 97% | 507.23 | 831 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 91% | 8.92 | 73 / 80 |
| peripheral blood | 84% | 637.04 | 785 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0032092 | Biological process | positive regulation of protein binding |
| GO_0042273 | Biological process | ribosomal large subunit biogenesis |
| GO_1904749 | Biological process | regulation of protein localization to nucleolus |
| GO_0042254 | Biological process | ribosome biogenesis |
| GO_0006364 | Biological process | rRNA processing |
| GO_0051973 | Biological process | positive regulation of telomerase activity |
| GO_0005730 | Cellular component | nucleolus |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0016020 | Cellular component | membrane |
| GO_0000176 | Cellular component | nuclear exosome (RNase complex) |
| GO_0005697 | Cellular component | telomerase holoenzyme complex |
| GO_0005634 | Cellular component | nucleus |
| GO_1990275 | Molecular function | preribosome binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0016887 | Molecular function | ATP hydrolysis activity |
| GO_0005524 | Molecular function | ATP binding |
| GO_0003723 | Molecular function | RNA binding |
| Gene name | NVL |
| Protein name | Nuclear VCP like Nuclear valosin-containing protein-like (NVLp) (Nuclear VCP-like protein) NVL protein Nuclear VCP-like protein |
| Synonyms | NVL2 |
| Description | FUNCTION: Participates in the assembly of the telomerase holoenzyme and effecting of telomerase activity via its interaction with TERT . Involved in both early and late stages of the pre-rRNA processing pathways . Spatiotemporally regulates 60S ribosomal subunit biogenesis in the nucleolus . Catalyzes the release of specific assembly factors, such as WDR74, from pre-60S ribosomal particles through the ATPase activity . . |
| Accessions | ENST00000436927.5 A0A087WV72 ENST00000469968.5 [O15381-3] E9PH71 ENST00000467882.5 ENST00000461546.2 E7EWK7 ENST00000340871.8 [O15381-4] E9PGD8 A0JLP9 ENST00000281701.11 [O15381-1] ENST00000492281.5 Q96PA2 ENST00000391875.6 [O15381-2] ENST00000470989.5 ENST00000488718.5 ENST00000469075.5 [O15381-5] ENST00000482491.5 [O15381-4] C9J6P7 O15381 ENST00000481213.5 C9JP83 F8WF01 |