Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell of lymphatic vessel | 8 studies | 21% ± 2% | |
retinal rod cell | 6 studies | 32% ± 9% | |
oligodendrocyte precursor cell | 6 studies | 29% ± 11% | |
fibroblast | 4 studies | 22% ± 3% | |
astrocyte | 4 studies | 30% ± 10% | |
endothelial cell | 3 studies | 27% ± 4% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
eye | 3 studies | 25% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
intestine | 100% | 2500.75 | 965 / 966 | 89% | 50.81 | 468 / 527 |
thymus | 100% | 3319.13 | 651 / 653 | 82% | 79.65 | 494 / 605 |
liver | 96% | 1802.86 | 218 / 226 | 80% | 29.37 | 325 / 406 |
brain | 76% | 1128.21 | 2020 / 2642 | 97% | 45.37 | 682 / 705 |
kidney | 88% | 1266.27 | 78 / 89 | 77% | 25.78 | 692 / 901 |
breast | 97% | 2441.34 | 444 / 459 | 65% | 14.13 | 723 / 1118 |
bladder | 100% | 2129.24 | 21 / 21 | 59% | 31.62 | 299 / 504 |
esophagus | 73% | 1194.06 | 1050 / 1445 | 85% | 46.79 | 155 / 183 |
ovary | 100% | 4132.59 | 180 / 180 | 54% | 15.89 | 231 / 430 |
uterus | 100% | 5748.65 | 170 / 170 | 51% | 20.52 | 232 / 459 |
stomach | 65% | 934.54 | 233 / 359 | 85% | 37.14 | 242 / 286 |
prostate | 96% | 1763.36 | 236 / 245 | 43% | 6.25 | 218 / 502 |
lung | 72% | 669.55 | 414 / 578 | 68% | 40.81 | 780 / 1155 |
skin | 80% | 7334.28 | 1439 / 1809 | 50% | 34.24 | 234 / 472 |
adrenal gland | 45% | 393.73 | 115 / 258 | 58% | 14.42 | 134 / 230 |
blood vessel | 100% | 4469.61 | 1335 / 1335 | 0% | 0 | 0 / 0 |
adipose | 98% | 2714.21 | 1185 / 1204 | 0% | 0 | 0 / 0 |
spleen | 98% | 1290.90 | 235 / 241 | 0% | 0 | 0 / 0 |
pancreas | 3% | 20.50 | 9 / 328 | 89% | 41.28 | 159 / 178 |
heart | 54% | 592.13 | 461 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 43% | 17.15 | 34 / 80 |
tonsil | 0% | 0 | 0 / 0 | 38% | 14.34 | 17 / 45 |
peripheral blood | 16% | 189.88 | 149 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 10% | 1.24 | 3 / 29 |
muscle | 7% | 63.89 | 60 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0055074 | Biological process | calcium ion homeostasis |
GO_0006196 | Biological process | AMP catabolic process |
GO_0033198 | Biological process | response to ATP |
GO_0046034 | Biological process | ATP metabolic process |
GO_0046086 | Biological process | adenosine biosynthetic process |
GO_0046032 | Biological process | ADP catabolic process |
GO_0050728 | Biological process | negative regulation of inflammatory response |
GO_0006259 | Biological process | DNA metabolic process |
GO_0140928 | Biological process | inhibition of non-skeletal tissue mineralization |
GO_0007159 | Biological process | leukocyte cell-cell adhesion |
GO_0009897 | Cellular component | external side of plasma membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005654 | Cellular component | nucleoplasm |
GO_0009986 | Cellular component | cell surface |
GO_0005829 | Cellular component | cytosol |
GO_0050484 | Molecular function | GMP 5'-nucleotidase activity |
GO_0042802 | Molecular function | identical protein binding |
GO_0000166 | Molecular function | nucleotide binding |
GO_0050483 | Molecular function | IMP 5'-nucleotidase activity |
GO_0008270 | Molecular function | zinc ion binding |
GO_0002953 | Molecular function | 5'-deoxynucleotidase activity |
GO_0050340 | Molecular function | thymidylate 5'-phosphatase activity |
GO_0106411 | Molecular function | XMP 5'-nucleosidase activity |
GO_0005515 | Molecular function | protein binding |
GO_0008253 | Molecular function | 5'-nucleotidase activity |
Gene name | NT5E |
Protein name | 5'-nucleotidase (EC 3.1.3.5) (Ecto-5'-nucleotidase) 5'-nucleotidase (EC 3.1.3.5) 5'-nucleotidase (5'-NT) (EC 3.1.3.35) (EC 3.1.3.5) (EC 3.1.3.89) (EC 3.1.3.91) (EC 3.1.3.99) (5'-deoxynucleotidase) (Ecto-5'-nucleotidase) (IMP-specific 5'-nucleotidase) (Thymidylate 5'-phosphatase) (CD antigen CD73) |
Synonyms | hCG_401111 NTE NT5 |
Description | FUNCTION: Catalyzes the hydrolysis of nucleotide monophosphates, releasing inorganic phosphate and the corresponding nucleoside, with AMP being the preferred substrate . Shows a preference for ribonucleotide monophosphates over their equivalent deoxyribose forms . Other substrates include IMP, UMP, GMP, CMP, dAMP, dCMP, dTMP, NAD and NMN . . |
Accessions | H0Y7R7 ENST00000369646.7 ENST00000437581.1 Q53Z63 ENST00000369651.7 [P21589-2] Q96B60 P21589 ENST00000257770.8 [P21589-1] H0Y3X5 ENST00000416334.5 Q6NZX3 |