Insufficient scRNA-seq data for expression of NPR2 at single-cell level.
Insufficient scRNA-seq data for expression of NPR2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 100% | 1773.56 | 180 / 180 | 97% | 12.11 | 418 / 430 |
kidney | 100% | 1102.01 | 89 / 89 | 94% | 9.59 | 851 / 901 |
prostate | 100% | 2170.43 | 245 / 245 | 94% | 7.03 | 470 / 502 |
brain | 94% | 1619.94 | 2478 / 2642 | 100% | 19.82 | 703 / 705 |
lung | 100% | 1789.71 | 577 / 578 | 92% | 8.11 | 1057 / 1155 |
intestine | 100% | 2245.72 | 964 / 966 | 91% | 5.28 | 480 / 527 |
skin | 98% | 1844.81 | 1775 / 1809 | 92% | 16.99 | 436 / 472 |
breast | 100% | 2004.15 | 459 / 459 | 89% | 6.65 | 997 / 1118 |
thymus | 100% | 1288.91 | 650 / 653 | 88% | 5.19 | 532 / 605 |
adrenal gland | 97% | 1413.29 | 251 / 258 | 82% | 15.17 | 189 / 230 |
bladder | 100% | 2383.14 | 21 / 21 | 79% | 4.26 | 398 / 504 |
stomach | 85% | 1264.72 | 305 / 359 | 91% | 5.55 | 260 / 286 |
liver | 84% | 782.74 | 190 / 226 | 88% | 12.29 | 357 / 406 |
esophagus | 86% | 1851.86 | 1238 / 1445 | 86% | 6.61 | 157 / 183 |
uterus | 100% | 4267.29 | 170 / 170 | 65% | 7.17 | 297 / 459 |
pancreas | 28% | 159.17 | 91 / 328 | 95% | 9.40 | 169 / 178 |
adipose | 100% | 2300.23 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 3405.24 | 1335 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 10.75 | 80 / 80 |
muscle | 99% | 1209.96 | 796 / 803 | 0% | 0 | 0 / 0 |
spleen | 99% | 913.76 | 238 / 241 | 0% | 0 | 0 / 0 |
heart | 98% | 1487.52 | 840 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 66% | 2.98 | 19 / 29 |
tonsil | 0% | 0 | 0 / 0 | 36% | 1.36 | 16 / 45 |
peripheral blood | 14% | 73.33 | 128 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0051447 | Biological process | negative regulation of meiotic cell cycle |
GO_1901653 | Biological process | cellular response to peptide |
GO_0007605 | Biological process | sensory perception of sound |
GO_0007283 | Biological process | spermatogenesis |
GO_0001974 | Biological process | blood vessel remodeling |
GO_0003417 | Biological process | growth plate cartilage development |
GO_0006182 | Biological process | cGMP biosynthetic process |
GO_0030540 | Biological process | female genitalia development |
GO_0048668 | Biological process | collateral sprouting |
GO_0000165 | Biological process | MAPK cascade |
GO_0001549 | Biological process | cumulus cell differentiation |
GO_0008217 | Biological process | regulation of blood pressure |
GO_0002062 | Biological process | chondrocyte differentiation |
GO_0035988 | Biological process | chondrocyte proliferation |
GO_0035264 | Biological process | multicellular organism growth |
GO_0001570 | Biological process | vasculogenesis |
GO_0060385 | Biological process | axonogenesis involved in innervation |
GO_0021647 | Biological process | vestibulocochlear nerve maturation |
GO_1900194 | Biological process | negative regulation of oocyte maturation |
GO_0071321 | Biological process | cellular response to cGMP |
GO_0001958 | Biological process | endochondral ossification |
GO_0060466 | Biological process | activation of meiosis involved in egg activation |
GO_0007033 | Biological process | vacuole organization |
GO_0097011 | Biological process | cellular response to granulocyte macrophage colony-stimulating factor stimulus |
GO_1902074 | Biological process | response to salt |
GO_0007168 | Biological process | receptor guanylyl cyclase signaling pathway |
GO_0061939 | Biological process | c-di-GMP signaling |
GO_0051402 | Biological process | neuron apoptotic process |
GO_0071774 | Biological process | response to fibroblast growth factor |
GO_0035483 | Biological process | gastric emptying |
GO_0036342 | Biological process | post-anal tail morphogenesis |
GO_0051276 | Biological process | chromosome organization |
GO_0007268 | Biological process | chemical synaptic transmission |
GO_0019228 | Biological process | neuronal action potential |
GO_0035108 | Biological process | limb morphogenesis |
GO_0035112 | Biological process | genitalia morphogenesis |
GO_0097194 | Biological process | execution phase of apoptosis |
GO_0007173 | Biological process | epidermal growth factor receptor signaling pathway |
GO_0001964 | Biological process | startle response |
GO_0061042 | Biological process | vascular wound healing |
GO_0034699 | Biological process | response to luteinizing hormone |
GO_0001945 | Biological process | lymph vessel development |
GO_0048546 | Biological process | digestive tract morphogenesis |
GO_0048745 | Biological process | smooth muscle tissue development |
GO_1903537 | Biological process | meiotic cell cycle process involved in oocyte maturation |
GO_0050872 | Biological process | white fat cell differentiation |
GO_0005886 | Cellular component | plasma membrane |
GO_0043005 | Cellular component | neuron projection |
GO_0005929 | Cellular component | cilium |
GO_0045202 | Cellular component | synapse |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0004016 | Molecular function | adenylate cyclase activity |
GO_0042562 | Molecular function | hormone binding |
GO_0017046 | Molecular function | peptide hormone binding |
GO_0042802 | Molecular function | identical protein binding |
GO_0004672 | Molecular function | protein kinase activity |
GO_0005525 | Molecular function | GTP binding |
GO_0016941 | Molecular function | natriuretic peptide receptor activity |
GO_0004383 | Molecular function | guanylate cyclase activity |
GO_0005524 | Molecular function | ATP binding |
GO_0005515 | Molecular function | protein binding |
Gene name | NPR2 |
Protein name | Atrial natriuretic peptide receptor 2 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type B) (ANP-B) (ANPR-B) (NPR-B) (Guanylate cyclase B) (GC-B) Guanylate cyclase (EC 4.6.1.2) Atrial natriuretic peptide receptor 2 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type B) (Guanylate cyclase B) Natriuretic peptide receptor 2 |
Synonyms | ANPRB |
Description | FUNCTION: Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth. . FUNCTION: Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth. . FUNCTION: Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth. . FUNCTION: Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth. . FUNCTION: Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth. . FUNCTION: Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth. . FUNCTION: Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth. . FUNCTION: Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth. . FUNCTION: Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth. . |
Accessions | A0A8I5QJG2 A0A8I5KTF2 ENST00000689898.1 A0A8I5QJT7 ENST00000685871.1 ENST00000690267.1 P20594 ENST00000687357.1 ENST00000448821.6 A0A8I5KSX8 A0A8I5KR63 H7C1X0 A0A8I5KVN5 A0A8I5KT66 ENST00000690070.1 ENST00000689788.1 ENST00000691969.1 A0A8I5KTJ8 ENST00000687787.1 A0A8I5KVW9 ENST00000693094.1 ENST00000692233.1 ENST00000421267.6 A6NJF2 ENST00000342694.7 [P20594-1] H7C1A1 |