Insufficient scRNA-seq data for expression of NEUROG3 at single-cell level.
Insufficient scRNA-seq data for expression of NEUROG3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
intestine | 87% | 32.27 | 842 / 966 | 25% | 2.08 | 134 / 527 |
adrenal gland | 76% | 6.09 | 196 / 258 | 2% | 0.09 | 4 / 230 |
stomach | 53% | 2.70 | 192 / 359 | 22% | 1.82 | 64 / 286 |
spleen | 71% | 3.36 | 170 / 241 | 0% | 0 | 0 / 0 |
lung | 63% | 3.40 | 364 / 578 | 7% | 1.55 | 85 / 1155 |
esophagus | 44% | 2.35 | 630 / 1445 | 22% | 6.94 | 40 / 183 |
adipose | 65% | 5.68 | 779 / 1204 | 0% | 0 | 0 / 0 |
brain | 53% | 14.09 | 1395 / 2642 | 9% | 0.14 | 60 / 705 |
pancreas | 41% | 1.63 | 133 / 328 | 10% | 0.39 | 17 / 178 |
blood vessel | 50% | 3.34 | 663 / 1335 | 0% | 0 | 0 / 0 |
breast | 43% | 1.93 | 196 / 459 | 4% | 0.39 | 46 / 1118 |
thymus | 45% | 2.06 | 293 / 653 | 0% | 0 | 0 / 605 |
kidney | 38% | 1.45 | 34 / 89 | 1% | 0.04 | 11 / 901 |
heart | 37% | 1.42 | 321 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 36% | 4.49 | 339 / 929 | 0% | 0 | 0 / 0 |
bladder | 29% | 1.10 | 6 / 21 | 5% | 0.40 | 27 / 504 |
prostate | 27% | 0.87 | 67 / 245 | 1% | 0.03 | 5 / 502 |
lymph node | 0% | 0 | 0 / 0 | 24% | 0.68 | 7 / 29 |
uterus | 21% | 0.55 | 35 / 170 | 2% | 0.08 | 11 / 459 |
ovary | 21% | 0.59 | 37 / 180 | 1% | 0.15 | 5 / 430 |
muscle | 17% | 0.44 | 137 / 803 | 0% | 0 | 0 / 0 |
skin | 11% | 0.28 | 194 / 1809 | 4% | 0.08 | 18 / 472 |
liver | 12% | 0.37 | 27 / 226 | 0% | 0.03 | 2 / 406 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0061564 | Biological process | axon development |
GO_0021510 | Biological process | spinal cord development |
GO_0048814 | Biological process | regulation of dendrite morphogenesis |
GO_0030855 | Biological process | epithelial cell differentiation |
GO_0030900 | Biological process | forebrain development |
GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
GO_0007422 | Biological process | peripheral nervous system development |
GO_0007417 | Biological process | central nervous system development |
GO_0030902 | Biological process | hindbrain development |
GO_0060290 | Biological process | transdifferentiation |
GO_0007399 | Biological process | nervous system development |
GO_0045666 | Biological process | positive regulation of neuron differentiation |
GO_0007423 | Biological process | sensory organ development |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0000785 | Cellular component | chromatin |
GO_0005634 | Cellular component | nucleus |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
GO_0001227 | Molecular function | DNA-binding transcription repressor activity, RNA polymerase II-specific |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
GO_0031490 | Molecular function | chromatin DNA binding |
GO_0070888 | Molecular function | E-box binding |
GO_0046983 | Molecular function | protein dimerization activity |
GO_0005515 | Molecular function | protein binding |
Gene name | NEUROG3 |
Protein name | Neurogenin 3 Neurogenin-3 (NGN-3) (Class A basic helix-loop-helix protein 7) (bHLHa7) (Protein atonal homolog 5) |
Synonyms | ATOH5 NGN3 BHLHA7 |
Description | FUNCTION: Acts as a transcriptional regulator. Together with NKX2-2, initiates transcriptional activation of NEUROD1. Involved in neurogenesis. Also required for the specification of a common precursor of the 4 pancreatic endocrine cell types (By similarity). . |
Accessions | Q9Y4Z2 E0X9P2 ENST00000242462.5 |