Name | Number of supported studies | Average coverage | |
---|---|---|---|
smooth muscle cell | 21 studies | 30% ± 15% | |
epithelial cell | 16 studies | 39% ± 19% | |
endothelial cell | 16 studies | 27% ± 11% | |
basal cell | 11 studies | 35% ± 20% | |
pericyte | 11 studies | 35% ± 15% | |
ciliated cell | 10 studies | 30% ± 15% | |
goblet cell | 8 studies | 31% ± 13% | |
adipocyte | 7 studies | 24% ± 6% | |
conventional dendritic cell | 7 studies | 22% ± 6% | |
dendritic cell | 6 studies | 30% ± 9% | |
type I pneumocyte | 6 studies | 22% ± 5% | |
club cell | 6 studies | 26% ± 15% | |
respiratory goblet cell | 6 studies | 21% ± 5% | |
secretory cell | 5 studies | 29% ± 5% | |
enterocyte | 5 studies | 20% ± 3% | |
duct epithelial cell | 4 studies | 25% ± 3% | |
squamous epithelial cell | 4 studies | 41% ± 19% | |
progenitor cell | 4 studies | 23% ± 8% | |
vein endothelial cell | 4 studies | 30% ± 14% | |
mucus secreting cell | 4 studies | 23% ± 3% | |
transit amplifying cell | 4 studies | 31% ± 20% | |
myofibroblast cell | 3 studies | 23% ± 6% | |
abnormal cell | 3 studies | 20% ± 4% | |
brush cell | 3 studies | 25% ± 10% | |
capillary endothelial cell | 3 studies | 31% ± 14% | |
mesothelial cell | 3 studies | 41% ± 17% | |
serous secreting cell | 3 studies | 26% ± 7% | |
endothelial cell of vascular tree | 3 studies | 30% ± 13% | |
connective tissue cell | 3 studies | 27% ± 8% | |
fibroblast | 3 studies | 18% ± 2% | |
hepatocyte | 3 studies | 29% ± 11% | |
erythroblast | 3 studies | 31% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 4372.88 | 245 / 245 | 100% | 122.78 | 502 / 502 |
stomach | 100% | 5781.16 | 359 / 359 | 100% | 115.33 | 285 / 286 |
intestine | 100% | 7520.94 | 963 / 966 | 99% | 131.88 | 524 / 527 |
esophagus | 100% | 9255.86 | 1445 / 1445 | 99% | 128.83 | 181 / 183 |
bladder | 100% | 6070.95 | 21 / 21 | 99% | 157.49 | 498 / 504 |
breast | 100% | 7195.03 | 459 / 459 | 98% | 151.15 | 1101 / 1118 |
uterus | 100% | 4933.61 | 170 / 170 | 98% | 145.62 | 451 / 459 |
lung | 97% | 2691.33 | 561 / 578 | 100% | 121.28 | 1151 / 1155 |
ovary | 98% | 3780.24 | 177 / 180 | 97% | 73.17 | 419 / 430 |
thymus | 99% | 3725.58 | 648 / 653 | 93% | 69.31 | 565 / 605 |
pancreas | 91% | 2761.17 | 300 / 328 | 98% | 141.21 | 174 / 178 |
kidney | 96% | 2463.97 | 85 / 89 | 77% | 49.47 | 693 / 901 |
brain | 94% | 2718.91 | 2479 / 2642 | 76% | 43.91 | 533 / 705 |
liver | 97% | 2592.58 | 220 / 226 | 68% | 27.82 | 275 / 406 |
skin | 90% | 4648.09 | 1621 / 1809 | 39% | 17.94 | 184 / 472 |
blood vessel | 100% | 12885.70 | 1335 / 1335 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 109.05 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 36.95 | 1 / 1 |
adipose | 99% | 4857.53 | 1193 / 1204 | 0% | 0 | 0 / 0 |
muscle | 89% | 2194.14 | 715 / 803 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 79% | 31.75 | 23 / 29 |
adrenal gland | 42% | 661.24 | 108 / 258 | 33% | 10.87 | 77 / 230 |
heart | 31% | 482.78 | 270 / 861 | 0% | 0 | 0 / 0 |
spleen | 29% | 431.86 | 70 / 241 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 26% | 14.29 | 21 / 80 |
peripheral blood | 19% | 460.48 | 177 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007165 | Biological process | signal transduction |
GO_0051056 | Biological process | regulation of small GTPase mediated signal transduction |
GO_0035556 | Biological process | intracellular signal transduction |
GO_0051451 | Biological process | myoblast migration |
GO_0035025 | Biological process | positive regulation of Rho protein signal transduction |
GO_0071479 | Biological process | cellular response to ionizing radiation |
GO_0043065 | Biological process | positive regulation of apoptotic process |
GO_0001558 | Biological process | regulation of cell growth |
GO_0043547 | Biological process | positive regulation of GTPase activity |
GO_0070301 | Biological process | cellular response to hydrogen peroxide |
GO_0005829 | Cellular component | cytosol |
GO_0005634 | Cellular component | nucleus |
GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
GO_0005515 | Molecular function | protein binding |
Gene name | NET1 |
Protein name | Epididymis secretory sperm binding protein (Neuroepithelial cell transforming gene 1, isoform CRA_b) (cDNA FLJ50843, highly similar to Neuroepithelial cell-transforming gene 1 protein) Neuroepithelial cell transforming gene 1, isoform CRA_a (cDNA, FLJ96638, Homo sapiens neuroepithelial cell transforming gene 1 (NET1), mRNA) Neuroepithelial cell transforming 1 NET1 Neuroepithelial cell-transforming gene 1 protein (Proto-oncogene p65 Net1) (Rho guanine nucleotide exchange factor 8) |
Synonyms | ARHGEF8 hCG_19072 |
Description | FUNCTION: Acts as a guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death. . |
Accessions | ENST00000380359.3 [Q7Z628-2] Q5SQI5 ENST00000355029.9 [Q7Z628-1] ENST00000449083.5 Q5SQI7 A0A2X0SFV4 Q5SQI6 Q7Z628 |