NDUFS1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006120Biological processmitochondrial electron transport, NADH to ubiquinone
GO_0055085Biological processtransmembrane transport
GO_0045333Biological processcellular respiration
GO_0046034Biological processATP metabolic process
GO_0042776Biological processproton motive force-driven mitochondrial ATP synthesis
GO_0072593Biological processreactive oxygen species metabolic process
GO_0051881Biological processregulation of mitochondrial membrane potential
GO_0008637Biological processapoptotic mitochondrial changes
GO_0032981Biological processmitochondrial respiratory chain complex I assembly
GO_0009060Biological processaerobic respiration
GO_0005739Cellular componentmitochondrion
GO_0005758Cellular componentmitochondrial intermembrane space
GO_0005743Cellular componentmitochondrial inner membrane
GO_0005759Cellular componentmitochondrial matrix
GO_0045271Cellular componentrespiratory chain complex I
GO_0009055Molecular functionelectron transfer activity
GO_0008137Molecular functionNADH dehydrogenase (ubiquinone) activity
GO_0046872Molecular functionmetal ion binding
GO_0051537Molecular function2 iron, 2 sulfur cluster binding
GO_0005515Molecular functionprotein binding
GO_0051539Molecular function4 iron, 4 sulfur cluster binding

IV. Literature review

[source]
Gene nameNDUFS1
Protein nameNADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (Complex I-75kD)
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (EC 7.1.1.2) (Complex I-75kD)
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (EC 7.1.1.2) (Complex I-75kD) (CI-75kD)
Complex I-75kD
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
SynonymshCG_17250
DescriptionFUNCTION: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor . Essential for catalysing the entry and efficient transfer of electrons within complex I . Plays a key role in the assembly and stability of complex I and participates in the association of complex I with ubiquinol-cytochrome reductase complex (Complex III) to form supercomplexes . .

AccessionsENST00000423725.5 [P28331-4]
ENST00000637298.1 [P28331-4]
ENST00000454195.1
ENST00000440274.5 [P28331-5]
E5KRK5
F8WDL5
ENST00000432169.5 [P28331-3]
ENST00000637008.1
ENST00000449699.5 [P28331-1]
ENST00000457011.5
P28331
ENST00000635748.2 [P28331-1]
ENST00000456284.5
B4DJ81
Q9P1A0
ENST00000636505.1 [P28331-1]
ENST00000637907.1
ENST00000455934.6 [P28331-2]
ENST00000637631.1 [P28331-3]
ENST00000637733.1 [P28331-2]
ENST00000636105.1
ENST00000637990.1 [P28331-5]
C9JPQ5
ENST00000233190.11 [P28331-1]