Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 15 studies | 28% ± 12% | |
fibroblast | 10 studies | 22% ± 5% | |
astrocyte | 9 studies | 32% ± 14% | |
glutamatergic neuron | 8 studies | 42% ± 20% | |
epithelial cell | 8 studies | 37% ± 12% | |
adipocyte | 8 studies | 26% ± 7% | |
oligodendrocyte | 8 studies | 30% ± 11% | |
smooth muscle cell | 7 studies | 18% ± 3% | |
ciliated cell | 7 studies | 27% ± 9% | |
pericyte | 7 studies | 22% ± 6% | |
macrophage | 7 studies | 29% ± 16% | |
neuron | 6 studies | 40% ± 11% | |
retinal ganglion cell | 6 studies | 43% ± 21% | |
basal cell | 6 studies | 29% ± 8% | |
oligodendrocyte precursor cell | 6 studies | 33% ± 17% | |
GABAergic neuron | 6 studies | 43% ± 16% | |
kidney loop of Henle epithelial cell | 5 studies | 20% ± 3% | |
amacrine cell | 5 studies | 25% ± 6% | |
retina horizontal cell | 5 studies | 27% ± 5% | |
retinal cone cell | 5 studies | 26% ± 7% | |
cardiac muscle cell | 5 studies | 35% ± 7% | |
endothelial cell of lymphatic vessel | 5 studies | 23% ± 6% | |
retinal bipolar neuron | 4 studies | 23% ± 5% | |
microglial cell | 4 studies | 27% ± 6% | |
myeloid cell | 4 studies | 20% ± 4% | |
retinal rod cell | 4 studies | 20% ± 1% | |
goblet cell | 4 studies | 26% ± 10% | |
interneuron | 4 studies | 55% ± 19% | |
ionocyte | 3 studies | 31% ± 9% | |
conventional dendritic cell | 3 studies | 42% ± 28% | |
lymphocyte | 3 studies | 19% ± 3% | |
Mueller cell | 3 studies | 18% ± 0% | |
OFF-bipolar cell | 3 studies | 22% ± 1% | |
ON-bipolar cell | 3 studies | 26% ± 2% | |
rod bipolar cell | 3 studies | 28% ± 3% | |
dendritic cell | 3 studies | 49% ± 27% | |
endothelial cell of vascular tree | 3 studies | 25% ± 6% | |
mast cell | 3 studies | 32% ± 20% | |
hepatocyte | 3 studies | 32% ± 19% | |
enteroendocrine cell | 3 studies | 22% ± 4% | |
transit amplifying cell | 3 studies | 32% ± 16% | |
granule cell | 3 studies | 23% ± 6% | |
erythroblast | 3 studies | 24% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
intestine | 100% | 5826.72 | 966 / 966 | 100% | 30.98 | 527 / 527 |
liver | 100% | 5114.50 | 226 / 226 | 100% | 24.25 | 406 / 406 |
stomach | 100% | 5077.69 | 359 / 359 | 100% | 30.96 | 286 / 286 |
esophagus | 100% | 5154.58 | 1444 / 1445 | 100% | 31.05 | 183 / 183 |
breast | 100% | 4342.14 | 459 / 459 | 100% | 30.40 | 1116 / 1118 |
ovary | 100% | 3021.32 | 180 / 180 | 100% | 19.83 | 429 / 430 |
brain | 100% | 5308.08 | 2632 / 2642 | 100% | 35.70 | 705 / 705 |
adrenal gland | 100% | 10104.12 | 258 / 258 | 100% | 29.42 | 229 / 230 |
prostate | 100% | 3304.76 | 244 / 245 | 100% | 28.07 | 501 / 502 |
kidney | 100% | 5502.63 | 89 / 89 | 99% | 31.50 | 893 / 901 |
thymus | 100% | 3882.84 | 651 / 653 | 99% | 22.16 | 601 / 605 |
lung | 99% | 3400.05 | 572 / 578 | 100% | 25.62 | 1155 / 1155 |
uterus | 100% | 3633.22 | 170 / 170 | 99% | 20.49 | 454 / 459 |
bladder | 100% | 4253.14 | 21 / 21 | 99% | 22.09 | 498 / 504 |
skin | 100% | 4945.50 | 1808 / 1809 | 97% | 31.27 | 460 / 472 |
pancreas | 95% | 2012.77 | 313 / 328 | 99% | 20.43 | 177 / 178 |
adipose | 100% | 4590.90 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 16.58 | 29 / 29 |
muscle | 100% | 18594.89 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 3047.49 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 25.68 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 8.13 | 1 / 1 |
blood vessel | 100% | 4245.78 | 1333 / 1335 | 0% | 0 | 0 / 0 |
heart | 98% | 14974.43 | 840 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 91% | 18.51 | 73 / 80 |
peripheral blood | 59% | 2159.83 | 549 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006120 | Biological process | mitochondrial electron transport, NADH to ubiquinone |
GO_0055085 | Biological process | transmembrane transport |
GO_0045333 | Biological process | cellular respiration |
GO_0046034 | Biological process | ATP metabolic process |
GO_0042776 | Biological process | proton motive force-driven mitochondrial ATP synthesis |
GO_0072593 | Biological process | reactive oxygen species metabolic process |
GO_0051881 | Biological process | regulation of mitochondrial membrane potential |
GO_0008637 | Biological process | apoptotic mitochondrial changes |
GO_0032981 | Biological process | mitochondrial respiratory chain complex I assembly |
GO_0009060 | Biological process | aerobic respiration |
GO_0005739 | Cellular component | mitochondrion |
GO_0005758 | Cellular component | mitochondrial intermembrane space |
GO_0005743 | Cellular component | mitochondrial inner membrane |
GO_0005759 | Cellular component | mitochondrial matrix |
GO_0045271 | Cellular component | respiratory chain complex I |
GO_0009055 | Molecular function | electron transfer activity |
GO_0008137 | Molecular function | NADH dehydrogenase (ubiquinone) activity |
GO_0046872 | Molecular function | metal ion binding |
GO_0051537 | Molecular function | 2 iron, 2 sulfur cluster binding |
GO_0005515 | Molecular function | protein binding |
GO_0051539 | Molecular function | 4 iron, 4 sulfur cluster binding |
Gene name | NDUFS1 |
Protein name | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (Complex I-75kD) NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (EC 7.1.1.2) (Complex I-75kD) NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (EC 7.1.1.2) (Complex I-75kD) (CI-75kD) Complex I-75kD NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial |
Synonyms | hCG_17250 |
Description | FUNCTION: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor . Essential for catalysing the entry and efficient transfer of electrons within complex I . Plays a key role in the assembly and stability of complex I and participates in the association of complex I with ubiquinol-cytochrome reductase complex (Complex III) to form supercomplexes . . |
Accessions | ENST00000423725.5 [P28331-4] ENST00000637298.1 [P28331-4] ENST00000454195.1 ENST00000440274.5 [P28331-5] E5KRK5 F8WDL5 ENST00000432169.5 [P28331-3] ENST00000637008.1 ENST00000449699.5 [P28331-1] ENST00000457011.5 P28331 ENST00000635748.2 [P28331-1] ENST00000456284.5 B4DJ81 Q9P1A0 ENST00000636505.1 [P28331-1] ENST00000637907.1 ENST00000455934.6 [P28331-2] ENST00000637631.1 [P28331-3] ENST00000637733.1 [P28331-2] ENST00000636105.1 ENST00000637990.1 [P28331-5] C9JPQ5 ENST00000233190.11 [P28331-1] |