Name | Number of supported studies | Average coverage | |
---|---|---|---|
fibroblast | 27 studies | 39% ± 14% | |
smooth muscle cell | 19 studies | 35% ± 14% | |
endothelial cell | 16 studies | 35% ± 18% | |
endothelial cell of lymphatic vessel | 13 studies | 36% ± 11% | |
glutamatergic neuron | 12 studies | 57% ± 24% | |
oligodendrocyte precursor cell | 12 studies | 31% ± 9% | |
myofibroblast cell | 11 studies | 37% ± 10% | |
pericyte | 11 studies | 29% ± 16% | |
astrocyte | 10 studies | 30% ± 9% | |
neuron | 9 studies | 38% ± 13% | |
GABAergic neuron | 9 studies | 53% ± 19% | |
connective tissue cell | 8 studies | 39% ± 13% | |
mesothelial cell | 7 studies | 26% ± 10% | |
epithelial cell | 7 studies | 30% ± 12% | |
retinal ganglion cell | 7 studies | 44% ± 16% | |
interneuron | 6 studies | 57% ± 14% | |
retinal cone cell | 6 studies | 31% ± 12% | |
amacrine cell | 5 studies | 25% ± 5% | |
adipocyte | 5 studies | 25% ± 6% | |
progenitor cell | 4 studies | 39% ± 19% | |
granule cell | 4 studies | 37% ± 5% | |
ciliated cell | 4 studies | 26% ± 8% | |
retinal rod cell | 4 studies | 29% ± 6% | |
renal principal cell | 4 studies | 35% ± 6% | |
abnormal cell | 3 studies | 34% ± 14% | |
neural crest cell | 3 studies | 27% ± 8% | |
GABAergic interneuron | 3 studies | 46% ± 10% | |
GABAergic amacrine cell | 3 studies | 35% ± 8% | |
OFF-bipolar cell | 3 studies | 24% ± 3% | |
ON-bipolar cell | 3 studies | 25% ± 5% | |
glycinergic amacrine cell | 3 studies | 28% ± 4% | |
chondrocyte | 3 studies | 29% ± 8% | |
erythroblast | 3 studies | 36% ± 11% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 100% | 8916.67 | 180 / 180 | 97% | 50.53 | 418 / 430 |
prostate | 98% | 5145.00 | 240 / 245 | 99% | 46.17 | 497 / 502 |
breast | 100% | 5748.40 | 458 / 459 | 96% | 37.93 | 1070 / 1118 |
thymus | 98% | 4853.68 | 641 / 653 | 96% | 78.36 | 582 / 605 |
lung | 100% | 24345.81 | 578 / 578 | 91% | 34.11 | 1050 / 1155 |
brain | 90% | 6080.06 | 2376 / 2642 | 99% | 61.88 | 696 / 705 |
adrenal gland | 97% | 4125.86 | 250 / 258 | 91% | 38.76 | 209 / 230 |
kidney | 99% | 6759.97 | 88 / 89 | 88% | 33.44 | 792 / 901 |
skin | 81% | 4511.34 | 1468 / 1809 | 95% | 85.68 | 450 / 472 |
bladder | 100% | 3555.86 | 21 / 21 | 74% | 21.53 | 372 / 504 |
uterus | 99% | 9040.88 | 169 / 170 | 74% | 30.58 | 340 / 459 |
esophagus | 79% | 2887.13 | 1138 / 1445 | 77% | 32.46 | 140 / 183 |
liver | 69% | 1987.66 | 157 / 226 | 60% | 12.82 | 244 / 406 |
intestine | 70% | 3073.44 | 677 / 966 | 43% | 9.65 | 228 / 527 |
pancreas | 19% | 485.32 | 62 / 328 | 90% | 27.09 | 161 / 178 |
blood vessel | 100% | 87436.39 | 1335 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 61.33 | 80 / 80 |
adipose | 99% | 6709.41 | 1194 / 1204 | 0% | 0 | 0 / 0 |
stomach | 45% | 2535.47 | 160 / 359 | 54% | 14.40 | 154 / 286 |
heart | 88% | 5869.81 | 761 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 56% | 13.67 | 25 / 45 |
lymph node | 0% | 0 | 0 / 0 | 28% | 4.24 | 8 / 29 |
spleen | 17% | 577.69 | 42 / 241 | 0% | 0 | 0 / 0 |
muscle | 11% | 304.99 | 85 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 6% | 266.63 | 59 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0030048 | Biological process | actin filament-based movement |
GO_0000281 | Biological process | mitotic cytokinesis |
GO_0007155 | Biological process | cell adhesion |
GO_0031032 | Biological process | actomyosin structure organization |
GO_0050714 | Biological process | positive regulation of protein secretion |
GO_0008360 | Biological process | regulation of cell shape |
GO_0030496 | Cellular component | midbody |
GO_0032982 | Cellular component | myosin filament |
GO_0070062 | Cellular component | extracellular exosome |
GO_0001725 | Cellular component | stress fiber |
GO_0016460 | Cellular component | myosin II complex |
GO_0005829 | Cellular component | cytosol |
GO_0005938 | Cellular component | cell cortex |
GO_0098871 | Cellular component | postsynaptic actin cytoskeleton |
GO_0005737 | Cellular component | cytoplasm |
GO_0032154 | Cellular component | cleavage furrow |
GO_0042641 | Cellular component | actomyosin |
GO_0097513 | Cellular component | myosin II filament |
GO_0030027 | Cellular component | lamellipodium |
GO_0016459 | Cellular component | myosin complex |
GO_0005634 | Cellular component | nucleus |
GO_0043531 | Molecular function | ADP binding |
GO_0048027 | Molecular function | mRNA 5'-UTR binding |
GO_0051015 | Molecular function | actin filament binding |
GO_0000146 | Molecular function | microfilament motor activity |
GO_0005524 | Molecular function | ATP binding |
GO_0005516 | Molecular function | calmodulin binding |
GO_0035613 | Molecular function | RNA stem-loop binding |
GO_0005515 | Molecular function | protein binding |
GO_0003779 | Molecular function | actin binding |
Gene name | MYH10 |
Protein name | Myosin heavy chain 10 Myosin-10 (Cellular myosin heavy chain, type B) (Myosin heavy chain 10) (Myosin heavy chain, non-muscle IIb) (Non-muscle myosin heavy chain B) (NMMHC-B) (Non-muscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) Nonmuscle myosin heavy chain 10 Myosin-10 |
Synonyms | |
Description | FUNCTION: Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the central part but not the margins of spreading cells), and lamellipodial extension; this function is mechanically antagonized by MYH9. . |
Accessions | ENST00000688497.1 ENST00000269243.8 [P35580-1] ENST00000687178.1 [P35580-5] ENST00000379980.8 [P35580-5] ENST00000360416.8 [P35580-4] ENST00000685418.1 ENST00000688902.1 [P35580-4] A0A8I5KSC2 ENST00000684843.1 P35580 ENST00000692526.1 ENST00000693441.1 [P35580-4] A5XEH4 A0A8I5KZ38 A0A8I5KTT7 ENST00000686654.1 [P35580-4] G1UI33 |