MYF5 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of MYF5 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of MYF5 at tissue level.

III. Associated gene sets

GO_0007519Biological processskeletal muscle tissue development
GO_0060415Biological processmuscle tissue morphogenesis
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0048704Biological processembryonic skeletal system morphogenesis
GO_0030198Biological processextracellular matrix organization
GO_0045663Biological processpositive regulation of myoblast differentiation
GO_0001952Biological processregulation of cell-matrix adhesion
GO_0042693Biological processmuscle cell fate commitment
GO_0007517Biological processmuscle organ development
GO_0001756Biological processsomitogenesis
GO_0043010Biological processcamera-type eye development
GO_0001503Biological processossification
GO_0035914Biological processskeletal muscle cell differentiation
GO_0001502Biological processcartilage condensation
GO_0048743Biological processpositive regulation of skeletal muscle fiber development
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0005654Cellular componentnucleoplasm
GO_0090575Cellular componentRNA polymerase II transcription regulator complex
GO_0000785Cellular componentchromatin
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0070888Molecular functionE-box binding
GO_0046983Molecular functionprotein dimerization activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameMYF5
Protein nameMyogenic factor 5 (Myf-5) (Class C basic helix-loop-helix protein 2) (bHLHc2)
SynonymsBHLHC2
DescriptionFUNCTION: Transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation . Together with MYOG and MYOD1, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein. .

AccessionsENST00000228644.4
P13349