Name | Number of supported studies | Average coverage | |
---|---|---|---|
non-classical monocyte | 5 studies | 24% ± 5% |
Insufficient scRNA-seq data for expression of MXD3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
uterus | 100% | 601.35 | 170 / 170 | 100% | 12.86 | 457 / 459 |
ovary | 100% | 489.99 | 180 / 180 | 98% | 8.16 | 423 / 430 |
bladder | 100% | 630.90 | 21 / 21 | 95% | 7.95 | 479 / 504 |
intestine | 100% | 767.43 | 966 / 966 | 93% | 6.32 | 488 / 527 |
esophagus | 100% | 749.72 | 1445 / 1445 | 92% | 4.44 | 168 / 183 |
stomach | 100% | 515.62 | 358 / 359 | 92% | 5.21 | 263 / 286 |
skin | 98% | 700.62 | 1772 / 1809 | 92% | 6.14 | 433 / 472 |
pancreas | 100% | 561.54 | 328 / 328 | 88% | 5.33 | 156 / 178 |
breast | 100% | 562.78 | 459 / 459 | 87% | 5.88 | 971 / 1118 |
lung | 100% | 763.17 | 577 / 578 | 86% | 4.43 | 989 / 1155 |
liver | 100% | 580.28 | 226 / 226 | 84% | 5.80 | 343 / 406 |
prostate | 100% | 919.02 | 245 / 245 | 73% | 3.40 | 366 / 502 |
brain | 86% | 208.18 | 2272 / 2642 | 79% | 6.75 | 560 / 705 |
adrenal gland | 97% | 378.86 | 251 / 258 | 64% | 3.59 | 148 / 230 |
kidney | 100% | 465.98 | 89 / 89 | 55% | 2.54 | 497 / 901 |
thymus | 100% | 701.68 | 653 / 653 | 55% | 7.40 | 332 / 605 |
lymph node | 0% | 0 | 0 / 0 | 100% | 21.25 | 29 / 29 |
spleen | 100% | 1661.31 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 10.07 | 1 / 1 |
peripheral blood | 100% | 2212.34 | 927 / 929 | 0% | 0 | 0 / 0 |
adipose | 100% | 469.28 | 1198 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 99% | 446.56 | 1324 / 1335 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 96% | 13.44 | 43 / 45 |
heart | 89% | 223.08 | 763 / 861 | 0% | 0 | 0 / 0 |
muscle | 76% | 179.16 | 609 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 57% | 1.95 | 46 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0090575 | Cellular component | RNA polymerase II transcription regulator complex |
GO_0000785 | Cellular component | chromatin |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_0046983 | Molecular function | protein dimerization activity |
GO_0005515 | Molecular function | protein binding |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
GO_0001227 | Molecular function | DNA-binding transcription repressor activity, RNA polymerase II-specific |
Gene name | MXD3 |
Protein name | Max dimerization protein 3 (Max dimerizer 3) (Class C basic helix-loop-helix protein 13) (bHLHc13) (Max-associated protein 3) (Max-interacting transcriptional repressor MAD3) (Myx) MAX dimerization protein 3 Max dimerization protein 3 (Max-associated protein 3) |
Synonyms | MAD3 BHLHC13 |
Description | FUNCTION: Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation (By similarity). . |
Accessions | ENST00000502529.1 ENST00000513169.1 Q05BW2 Q9BW11 D6RED4 ENST00000423571.6 [Q9BW11-4] ENST00000439742.7 [Q9BW11-1] ENST00000427908.6 [Q9BW11-3] D6RD21 ENST00000513063.5 [Q9BW11-1] |