Name | Number of supported studies | Average coverage | |
---|---|---|---|
classical monocyte | 25 studies | 37% ± 13% | |
macrophage | 21 studies | 28% ± 12% | |
monocyte | 19 studies | 36% ± 18% | |
conventional dendritic cell | 18 studies | 26% ± 9% | |
non-classical monocyte | 16 studies | 33% ± 9% | |
neutrophil | 14 studies | 62% ± 14% | |
dendritic cell | 12 studies | 31% ± 12% | |
myeloid cell | 9 studies | 31% ± 13% | |
epithelial cell | 7 studies | 37% ± 16% | |
natural killer cell | 6 studies | 21% ± 6% | |
mononuclear phagocyte | 5 studies | 26% ± 3% | |
enterocyte | 5 studies | 28% ± 6% | |
astrocyte | 5 studies | 24% ± 6% | |
squamous epithelial cell | 4 studies | 65% ± 13% | |
monocyte-derived dendritic cell | 4 studies | 35% ± 14% | |
goblet cell | 4 studies | 22% ± 4% | |
Mueller cell | 4 studies | 28% ± 8% | |
glutamatergic neuron | 4 studies | 47% ± 19% | |
oligodendrocyte | 4 studies | 22% ± 5% | |
hematopoietic precursor cell | 3 studies | 29% ± 12% | |
tissue-resident macrophage | 3 studies | 25% ± 5% | |
intermediate monocyte | 3 studies | 40% ± 10% | |
GABAergic neuron | 3 studies | 45% ± 10% | |
leukocyte | 3 studies | 26% ± 5% | |
brush cell | 3 studies | 30% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 99% | 12494.51 | 1427 / 1445 | 99% | 71.77 | 182 / 183 |
lung | 100% | 10024.23 | 577 / 578 | 98% | 26.25 | 1136 / 1155 |
bladder | 100% | 3382.62 | 21 / 21 | 94% | 25.22 | 475 / 504 |
intestine | 87% | 3552.68 | 843 / 966 | 99% | 35.16 | 523 / 527 |
breast | 89% | 2023.27 | 407 / 459 | 95% | 15.88 | 1064 / 1118 |
thymus | 98% | 2293.94 | 640 / 653 | 85% | 9.12 | 512 / 605 |
stomach | 83% | 2790.67 | 298 / 359 | 98% | 37.05 | 281 / 286 |
uterus | 82% | 1841.02 | 140 / 170 | 95% | 36.26 | 435 / 459 |
ovary | 91% | 1546.20 | 163 / 180 | 86% | 10.05 | 369 / 430 |
prostate | 88% | 1549.91 | 215 / 245 | 81% | 7.61 | 409 / 502 |
brain | 60% | 1187.73 | 1594 / 2642 | 97% | 12.67 | 684 / 705 |
kidney | 69% | 1495.25 | 61 / 89 | 87% | 10.66 | 787 / 901 |
skin | 73% | 2322.68 | 1318 / 1809 | 65% | 5.84 | 305 / 472 |
pancreas | 17% | 260.18 | 56 / 328 | 98% | 31.36 | 175 / 178 |
adrenal gland | 39% | 543.74 | 100 / 258 | 68% | 7.45 | 157 / 230 |
liver | 67% | 1464.15 | 151 / 226 | 36% | 3.80 | 146 / 406 |
spleen | 100% | 9280.84 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 43.18 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 8.20 | 1 / 1 |
peripheral blood | 97% | 54874.93 | 900 / 929 | 0% | 0 | 0 / 0 |
adipose | 94% | 2653.05 | 1134 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 90% | 1980.97 | 1201 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 48% | 5.45 | 14 / 29 |
heart | 46% | 977.48 | 397 / 861 | 0% | 0 | 0 / 0 |
muscle | 38% | 565.99 | 309 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 8% | 0.56 | 6 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0070443 | Cellular component | Mad-Max complex |
GO_0005739 | Cellular component | mitochondrion |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0000785 | Cellular component | chromatin |
GO_0005634 | Cellular component | nucleus |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_0046983 | Molecular function | protein dimerization activity |
GO_0005515 | Molecular function | protein binding |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
GO_0001227 | Molecular function | DNA-binding transcription repressor activity, RNA polymerase II-specific |
Gene name | MXD1 |
Protein name | Max dimerization protein 1 (Max dimerizer 1) (Protein MAD) MAX dimerization protein 1 MXD1 protein |
Synonyms | MAD |
Description | FUNCTION: Component of a transcriptional repressor complex together with MAX . In complex with MAX binds to the core DNA sequence 5'-CAC[GA]TG-3' . Antagonizes MYC transcriptional activity by competing with MYC for MAX binding . Binds to the TERT promoter and represses telomerase expression, possibly by interfering with MYC binding . . |
Accessions | F8WBI0 ENST00000435990.5 C9JBE8 B7ZLI7 ENST00000540449.5 [Q05195-2] ENST00000409442.2 ENST00000264444.7 [Q05195-1] Q05195 |