MTUS1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0010758Biological processregulation of macrophage chemotaxis
GO_0005730Cellular componentnucleolus
GO_0005813Cellular componentcentrosome
GO_0005615Cellular componentextracellular space
GO_0015630Cellular componentmicrotubule cytoskeleton
GO_0005794Cellular componentGolgi apparatus
GO_0005886Cellular componentplasma membrane
GO_0005874Cellular componentmicrotubule
GO_0005819Cellular componentspindle
GO_0005737Cellular componentcytoplasm
GO_0005739Cellular componentmitochondrion
GO_0005634Cellular componentnucleus
GO_0008017Molecular functionmicrotubule binding

IV. Literature review

[source]
Gene nameMTUS1
Protein nameMicrotubule associated scaffold protein 1
Microtubule-associated tumor suppressor 1 (AT2 receptor-binding protein) (Angiotensin-II type 2 receptor-interacting protein) (Mitochondrial tumor suppressor 1)
SynonymsGK1
ATBP
ATIP
KIAA1288
MTSG1
DescriptionFUNCTION: Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation. Isoform 1 inhibits breast cancer cell proliferation, delays the progression of mitosis by prolonging metaphase and reduces tumor growth. .

AccessionsENST00000262102.10 [Q9ULD2-1]
ENST00000693296.1 [Q9ULD2-1]
H0YC63
ENST00000381869.5 [Q9ULD2-2]
ENST00000634613.1 [Q9ULD2-4]
Q9ULD2
ENST00000297488.10 [Q9ULD2-3]
ENST00000381861.7 [Q9ULD2-6]
ENST00000519263.5 [Q9ULD2-2]
ENST00000544260.3 [Q9ULD2-7]
A0A0U1RQI2
ENST00000520196.5
ENST00000519066.5