MSC report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of MSC at tissue level.

III. Associated gene sets

GO_0003161Biological processcardiac conduction system development
GO_0007519Biological processskeletal muscle tissue development
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_1990830Biological processcellular response to leukemia inhibitory factor
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0060539Biological processdiaphragm development
GO_0014707Biological processbranchiomeric skeletal muscle development
GO_0060021Biological processroof of mouth development
GO_0006355Biological processregulation of DNA-templated transcription
GO_0005654Cellular componentnucleoplasm
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0000977Molecular functionRNA polymerase II transcription regulatory region sequence-specific DNA binding
GO_0001227Molecular functionDNA-binding transcription repressor activity, RNA polymerase II-specific
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0003700Molecular functionDNA-binding transcription factor activity
GO_0046983Molecular functionprotein dimerization activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameMSC
Protein nameMusculin (Activated B-cell factor 1) (ABF-1) (Class A basic helix-loop-helix protein 22) (bHLHa22)
SynonymsABF1
BHLHA22
DescriptionFUNCTION: Transcription repressor capable of inhibiting the transactivation capability of TCF3/E47. May play a role in regulating antigen-dependent B-cell differentiation.

AccessionsO60682
ENST00000325509.5