MRC1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0071222Biological processcellular response to lipopolysaccharide
GO_0046718Biological processsymbiont entry into host cell
GO_0071353Biological processcellular response to interleukin-4
GO_0006898Biological processreceptor-mediated endocytosis
GO_0071346Biological processcellular response to type II interferon
GO_0010008Cellular componentendosome membrane
GO_0009986Cellular componentcell surface
GO_0005886Cellular componentplasma membrane
GO_0004888Molecular functiontransmembrane signaling receptor activity
GO_0005537Molecular functionD-mannose binding
GO_0038023Molecular functionsignaling receptor activity
GO_0038024Molecular functioncargo receptor activity
GO_0005515Molecular functionprotein binding
GO_0001618Molecular functionvirus receptor activity

IV. Literature review

[source]
Gene nameMRC1
Protein nameMacrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206)
Alternative protein MRC1
SynonymsMRC1L1
CLEC13D
CLEC13DL
DescriptionFUNCTION: Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains.; FUNCTION: (Microbial infection) Acts as a phagocytic receptor for bacteria, fungi and other pathogens.; FUNCTION: (Microbial infection) Acts as a receptor for Dengue virus envelope protein E. .; FUNCTION: (Microbial infection) Interacts with Hepatitis B virus envelope protein. .

AccessionsL8E7Q9
P22897
ENST00000569591.3 [P22897-1]