Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| macrophage | 36 studies | 57% ± 20% | |
| endothelial cell of lymphatic vessel | 18 studies | 41% ± 15% | |
| myeloid cell | 11 studies | 46% ± 23% | |
| dendritic cell | 9 studies | 37% ± 15% | |
| alveolar macrophage | 8 studies | 82% ± 8% | |
| monocyte | 8 studies | 28% ± 10% | |
| conventional dendritic cell | 8 studies | 30% ± 7% | |
| microglial cell | 8 studies | 27% ± 9% | |
| endothelial cell of sinusoid | 5 studies | 50% ± 26% | |
| mononuclear phagocyte | 4 studies | 43% ± 8% | |
| non-classical monocyte | 4 studies | 18% ± 3% | |
| leukocyte | 3 studies | 23% ± 3% | |
| tissue-resident macrophage | 3 studies | 60% ± 21% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| lung | 6 studies | 20% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 100% | 10321.35 | 576 / 578 | 87% | 39.79 | 1005 / 1155 |
| thymus | 83% | 1318.27 | 542 / 653 | 74% | 12.75 | 450 / 605 |
| adrenal gland | 97% | 3401.62 | 251 / 258 | 58% | 7.51 | 133 / 230 |
| intestine | 93% | 2234.98 | 900 / 966 | 58% | 11.55 | 306 / 527 |
| bladder | 90% | 1679.14 | 19 / 21 | 60% | 15.51 | 301 / 504 |
| liver | 82% | 2341.02 | 186 / 226 | 64% | 13.67 | 258 / 406 |
| breast | 90% | 2588.86 | 412 / 459 | 55% | 9.05 | 618 / 1118 |
| stomach | 63% | 1199.59 | 225 / 359 | 65% | 11.80 | 187 / 286 |
| pancreas | 34% | 333.59 | 113 / 328 | 89% | 35.77 | 159 / 178 |
| esophagus | 60% | 1328.55 | 862 / 1445 | 57% | 8.82 | 104 / 183 |
| kidney | 53% | 936.49 | 47 / 89 | 62% | 12.25 | 562 / 901 |
| skin | 36% | 428.79 | 655 / 1809 | 65% | 11.99 | 306 / 472 |
| spleen | 100% | 8588.88 | 241 / 241 | 0% | 0 | 0 / 0 |
| uterus | 55% | 864.87 | 94 / 170 | 43% | 6.30 | 199 / 459 |
| adipose | 99% | 6721.13 | 1186 / 1204 | 0% | 0 | 0 / 0 |
| ovary | 57% | 933.74 | 103 / 180 | 34% | 3.50 | 146 / 430 |
| blood vessel | 78% | 2239.38 | 1038 / 1335 | 0% | 0 | 0 / 0 |
| prostate | 39% | 374.19 | 95 / 245 | 38% | 3.09 | 190 / 502 |
| lymph node | 0% | 0 | 0 / 0 | 69% | 11.05 | 20 / 29 |
| brain | 4% | 33.05 | 116 / 2642 | 50% | 7.91 | 355 / 705 |
| tonsil | 0% | 0 | 0 / 0 | 51% | 10.91 | 23 / 45 |
| heart | 50% | 820.00 | 433 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 21% | 1.42 | 17 / 80 |
| muscle | 14% | 127.88 | 114 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 10% | 154.47 | 91 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0071222 | Biological process | cellular response to lipopolysaccharide |
| GO_0046718 | Biological process | symbiont entry into host cell |
| GO_0071353 | Biological process | cellular response to interleukin-4 |
| GO_0006898 | Biological process | receptor-mediated endocytosis |
| GO_0071346 | Biological process | cellular response to type II interferon |
| GO_0010008 | Cellular component | endosome membrane |
| GO_0009986 | Cellular component | cell surface |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0004888 | Molecular function | transmembrane signaling receptor activity |
| GO_0005537 | Molecular function | D-mannose binding |
| GO_0038023 | Molecular function | signaling receptor activity |
| GO_0038024 | Molecular function | cargo receptor activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0001618 | Molecular function | virus receptor activity |
| Gene name | MRC1 |
| Protein name | Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) Alternative protein MRC1 |
| Synonyms | MRC1L1 CLEC13D CLEC13DL |
| Description | FUNCTION: Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains.; FUNCTION: (Microbial infection) Acts as a phagocytic receptor for bacteria, fungi and other pathogens.; FUNCTION: (Microbial infection) Acts as a receptor for Dengue virus envelope protein E. .; FUNCTION: (Microbial infection) Interacts with Hepatitis B virus envelope protein. . |
| Accessions | L8E7Q9 P22897 ENST00000569591.3 [P22897-1] |