MPRIP report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0015629Cellular componentactin cytoskeleton
GO_0005829Cellular componentcytosol
GO_0005925Cellular componentfocal adhesion
GO_0045296Molecular functioncadherin binding
GO_0051015Molecular functionactin filament binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameMPRIP
Protein nameMyosin phosphatase Rho interacting protein
Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)
MPRIP protein
SynonymsMRIP
KIAA0864
RHOIP3
DescriptionFUNCTION: Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells. .

AccessionsENST00000577514.5
ENST00000584067.5
A8MZF8
Q6WCQ1
H0Y2S9
ENST00000466186.2
ENST00000651222.2
J3KSW8
J3QRL2
B9EGI2
A0A1W2PPU9
J3QL44
ENST00000341712.8 [Q6WCQ1-1]
ENST00000579832.1
Q96EE5
H0Y7E2
A0A494BZV2
ENST00000313485.10
H7C3G6
ENST00000414263.5
ENST00000395806.5
ENST00000462033.1
ENST00000578209.5
J3KSK7
K7EJ14
ENST00000429184.7
K7EL39
ENST00000579361.1
ENST00000395811.9 [Q6WCQ1-2]