Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 19 studies | 25% ± 9% | |
| endothelial cell of lymphatic vessel | 13 studies | 28% ± 11% | |
| smooth muscle cell | 11 studies | 22% ± 4% | |
| type I pneumocyte | 10 studies | 27% ± 9% | |
| glutamatergic neuron | 10 studies | 37% ± 23% | |
| oligodendrocyte | 10 studies | 32% ± 10% | |
| fibroblast | 9 studies | 21% ± 6% | |
| ciliated cell | 9 studies | 27% ± 12% | |
| astrocyte | 9 studies | 28% ± 10% | |
| GABAergic neuron | 7 studies | 40% ± 20% | |
| epithelial cell | 7 studies | 32% ± 15% | |
| retinal rod cell | 7 studies | 22% ± 3% | |
| capillary endothelial cell | 6 studies | 17% ± 1% | |
| myofibroblast cell | 6 studies | 18% ± 2% | |
| retinal ganglion cell | 6 studies | 45% ± 23% | |
| oligodendrocyte precursor cell | 6 studies | 25% ± 9% | |
| pericyte | 6 studies | 18% ± 3% | |
| neuron | 5 studies | 39% ± 13% | |
| basal cell | 5 studies | 30% ± 20% | |
| retinal cone cell | 5 studies | 37% ± 13% | |
| cardiac muscle cell | 5 studies | 26% ± 5% | |
| microglial cell | 5 studies | 25% ± 6% | |
| amacrine cell | 4 studies | 29% ± 7% | |
| lymphocyte | 4 studies | 21% ± 3% | |
| Mueller cell | 4 studies | 26% ± 3% | |
| abnormal cell | 4 studies | 21% ± 3% | |
| macrophage | 4 studies | 20% ± 5% | |
| interneuron | 4 studies | 48% ± 19% | |
| glomerular endothelial cell | 3 studies | 20% ± 0% | |
| myeloid cell | 3 studies | 19% ± 1% | |
| retina horizontal cell | 3 studies | 17% ± 2% | |
| OFF-bipolar cell | 3 studies | 26% ± 11% | |
| rod bipolar cell | 3 studies | 17% ± 1% | |
| endothelial cell of vascular tree | 3 studies | 25% ± 5% | |
| regulatory T cell | 3 studies | 17% ± 2% | |
| club cell | 3 studies | 21% ± 4% | |
| Schwann cell | 3 studies | 28% ± 10% | |
| goblet cell | 3 studies | 37% ± 22% | |
| mesothelial cell | 3 studies | 35% ± 9% | |
| granule cell | 3 studies | 34% ± 10% | |
| connective tissue cell | 3 studies | 27% ± 13% | |
| renal principal cell | 3 studies | 23% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 2773.52 | 1445 / 1445 | 100% | 14.66 | 183 / 183 |
| brain | 100% | 3593.79 | 2642 / 2642 | 99% | 17.05 | 701 / 705 |
| lung | 100% | 2633.78 | 577 / 578 | 99% | 10.94 | 1147 / 1155 |
| prostate | 100% | 2772.74 | 245 / 245 | 99% | 16.76 | 497 / 502 |
| kidney | 100% | 2299.87 | 89 / 89 | 98% | 20.39 | 885 / 901 |
| thymus | 100% | 2384.55 | 653 / 653 | 98% | 13.33 | 590 / 605 |
| breast | 100% | 2313.45 | 459 / 459 | 97% | 14.37 | 1085 / 1118 |
| ovary | 100% | 2276.74 | 180 / 180 | 96% | 8.99 | 411 / 430 |
| uterus | 100% | 2929.96 | 170 / 170 | 94% | 10.19 | 430 / 459 |
| adrenal gland | 100% | 1371.02 | 257 / 258 | 94% | 12.38 | 216 / 230 |
| pancreas | 94% | 860.64 | 308 / 328 | 98% | 13.69 | 175 / 178 |
| bladder | 100% | 2832.71 | 21 / 21 | 90% | 12.02 | 456 / 504 |
| skin | 100% | 2374.89 | 1805 / 1809 | 90% | 14.62 | 427 / 472 |
| stomach | 100% | 1510.96 | 359 / 359 | 86% | 8.18 | 245 / 286 |
| intestine | 100% | 2116.09 | 965 / 966 | 76% | 6.23 | 401 / 527 |
| liver | 86% | 677.08 | 195 / 226 | 46% | 3.54 | 188 / 406 |
| blood vessel | 100% | 3330.63 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 9.90 | 1 / 1 |
| adipose | 100% | 2592.99 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1440.22 | 240 / 241 | 0% | 0 | 0 / 0 |
| heart | 98% | 2209.61 | 841 / 861 | 0% | 0 | 0 / 0 |
| muscle | 93% | 884.16 | 749 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 91% | 7.56 | 41 / 45 |
| eye | 0% | 0 | 0 / 0 | 66% | 7.09 | 53 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 59% | 3.09 | 17 / 29 |
| peripheral blood | 58% | 727.57 | 536 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0071108 | Biological process | protein K48-linked deubiquitination |
| GO_0006508 | Biological process | proteolysis |
| GO_0008150 | Biological process | biological_process |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0036435 | Molecular function | K48-linked polyubiquitin modification-dependent protein binding |
| GO_0071795 | Molecular function | K11-linked polyubiquitin modification-dependent protein binding |
| GO_0071796 | Molecular function | K6-linked polyubiquitin modification-dependent protein binding |
| GO_0016807 | Molecular function | cysteine-type carboxypeptidase activity |
| GO_0070530 | Molecular function | K63-linked polyubiquitin modification-dependent protein binding |
| GO_0004843 | Molecular function | cysteine-type deubiquitinase activity |
| GO_1990380 | Molecular function | K48-linked deubiquitinase activity |
| Gene name | MINDY2 |
| Protein name | Ubiquitin carboxyl-terminal hydrolase (EC 3.4.19.12) Ubiquitin carboxyl-terminal hydrolase MINDY-2 (EC 3.4.19.12) (Deubiquitinating enzyme MINDY-2) (Protein FAM63B) |
| Synonyms | hCG_40045 FAM63B KIAA1164 |
| Description | FUNCTION: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins . Binds to polyubiquitin chains of different linkage types, including 'Lys-6', 'Lys-11', 'Lys-29', 'Lys-33', 'Lys-48' and 'Lys-63' . May play a regulatory role at the level of protein turnover . . FUNCTION: Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins. Has exodeubiquitinase activity and has a preference for long polyubiquitin chains. May play a regulatory role at the level of protein turnover. . FUNCTION: Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins. Has exodeubiquitinase activity and has a preference for long polyubiquitin chains. May play a regulatory role at the level of protein turnover. . |
| Accessions | ENST00000316848.9 J3KNL7 H0YM15 ENST00000560289.5 Q8NBR6 ENST00000450403.3 [Q8NBR6-2] ENST00000559228.6 [Q8NBR6-1] |