Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 13 studies | 30% ± 14% | |
fibroblast | 10 studies | 28% ± 8% | |
astrocyte | 10 studies | 43% ± 19% | |
adipocyte | 9 studies | 36% ± 5% | |
ciliated cell | 8 studies | 33% ± 13% | |
epithelial cell | 7 studies | 34% ± 18% | |
oligodendrocyte precursor cell | 6 studies | 25% ± 8% | |
retina horizontal cell | 6 studies | 47% ± 15% | |
basal cell | 6 studies | 29% ± 13% | |
endothelial cell of lymphatic vessel | 6 studies | 36% ± 9% | |
type I pneumocyte | 6 studies | 34% ± 11% | |
glutamatergic neuron | 5 studies | 31% ± 14% | |
Mueller cell | 5 studies | 39% ± 17% | |
interneuron | 4 studies | 38% ± 12% | |
neuron | 4 studies | 40% ± 19% | |
GABAergic neuron | 4 studies | 44% ± 7% | |
club cell | 4 studies | 29% ± 8% | |
type II pneumocyte | 4 studies | 22% ± 5% | |
granule cell | 3 studies | 26% ± 2% | |
progenitor cell | 3 studies | 30% ± 4% | |
amacrine cell | 3 studies | 31% ± 2% | |
mesothelial cell | 3 studies | 32% ± 11% | |
GABAergic amacrine cell | 3 studies | 32% ± 6% | |
abnormal cell | 3 studies | 34% ± 17% | |
retinal pigment epithelial cell | 3 studies | 32% ± 10% | |
connective tissue cell | 3 studies | 28% ± 9% | |
ependymal cell | 3 studies | 41% ± 7% | |
respiratory goblet cell | 3 studies | 33% ± 12% | |
transit amplifying cell | 3 studies | 32% ± 20% | |
renal principal cell | 3 studies | 27% ± 5% | |
mucus secreting cell | 3 studies | 29% ± 8% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 1569.39 | 1445 / 1445 | 98% | 15.97 | 180 / 183 |
intestine | 100% | 3755.49 | 966 / 966 | 98% | 13.17 | 518 / 527 |
bladder | 100% | 3004.24 | 21 / 21 | 97% | 16.56 | 487 / 504 |
uterus | 100% | 2218.32 | 170 / 170 | 95% | 18.16 | 438 / 459 |
stomach | 97% | 938.75 | 347 / 359 | 97% | 13.29 | 276 / 286 |
lung | 100% | 1993.53 | 578 / 578 | 93% | 13.24 | 1071 / 1155 |
brain | 96% | 1193.93 | 2525 / 2642 | 96% | 11.14 | 678 / 705 |
prostate | 100% | 2262.84 | 245 / 245 | 91% | 9.96 | 455 / 502 |
ovary | 100% | 1340.63 | 180 / 180 | 90% | 8.75 | 387 / 430 |
kidney | 100% | 1793.80 | 89 / 89 | 88% | 16.32 | 789 / 901 |
skin | 98% | 1123.53 | 1775 / 1809 | 80% | 11.27 | 377 / 472 |
pancreas | 80% | 556.86 | 264 / 328 | 94% | 9.52 | 167 / 178 |
adrenal gland | 100% | 761.31 | 258 / 258 | 59% | 3.23 | 136 / 230 |
thymus | 100% | 1449.40 | 652 / 653 | 53% | 3.87 | 323 / 605 |
breast | 100% | 1711.41 | 459 / 459 | 47% | 4.76 | 527 / 1118 |
liver | 69% | 363.80 | 156 / 226 | 61% | 4.90 | 248 / 406 |
tonsil | 0% | 0 | 0 / 0 | 100% | 16.67 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 7.91 | 1 / 1 |
adipose | 100% | 1513.99 | 1203 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 97% | 1539.01 | 1298 / 1335 | 0% | 0 | 0 / 0 |
heart | 92% | 1427.39 | 796 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 46% | 4.31 | 37 / 80 |
spleen | 11% | 43.51 | 27 / 241 | 0% | 0 | 0 / 0 |
muscle | 8% | 31.74 | 61 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0.67 | 1 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0032874 | Biological process | positive regulation of stress-activated MAPK cascade |
GO_0007026 | Biological process | negative regulation of microtubule depolymerization |
GO_0035372 | Biological process | protein localization to microtubule |
GO_0000226 | Biological process | microtubule cytoskeleton organization |
GO_0070507 | Biological process | regulation of microtubule cytoskeleton organization |
GO_0007389 | Biological process | pattern specification process |
GO_0034451 | Cellular component | centriolar satellite |
GO_0005874 | Cellular component | microtubule |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0005829 | Cellular component | cytosol |
GO_0005881 | Cellular component | cytoplasmic microtubule |
GO_0005737 | Cellular component | cytoplasm |
GO_0005875 | Cellular component | microtubule associated complex |
GO_0005819 | Cellular component | spindle |
GO_0019899 | Molecular function | enzyme binding |
GO_0042803 | Molecular function | protein homodimerization activity |
GO_0016740 | Molecular function | transferase activity |
GO_0031625 | Molecular function | ubiquitin protein ligase binding |
GO_0042802 | Molecular function | identical protein binding |
GO_0008270 | Molecular function | zinc ion binding |
GO_0008017 | Molecular function | microtubule binding |
GO_0051219 | Molecular function | phosphoprotein binding |
GO_0005515 | Molecular function | protein binding |
Gene name | MID1 |
Protein name | Midline 1 E3 ubiquitin-protein ligase Midline-1 (EC 2.3.2.27) (RING finger protein Midline-1) (RING-type E3 ubiquitin transferase Midline-1) (Tripartite motif-containing protein 18) E3 ubiquitin-protein ligase Midline-1 (EC 2.3.2.27) (Midin) (Putative transcription factor XPRF) (RING finger protein 59) (RING finger protein Midline-1) (RING-type E3 ubiquitin transferase Midline-1) (Tripartite motif-containing protein 18) RING-type E3 ubiquitin transferase (EC 2.3.2.27) |
Synonyms | RNF59 XPRF FXY TRIM18 |
Description | FUNCTION: Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination. . FUNCTION: Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination. . FUNCTION: Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination. . FUNCTION: Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination. . FUNCTION: Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination. . |
Accessions | A0A6Q8PF94 ENST00000413894.5 A0A087X255 ENST00000453318.6 [O15344-1] ENST00000675073.1 ENST00000690004.1 ENST00000380782.6 [O15344-2] ENST00000413894.6 [O15344-1] A0A8I5KR14 ENST00000687008.1 ENST00000691943.1 ENST00000380785.5 [O15344-1] ENST00000689773.1 ENST00000674917.1 ENST00000317552.9 [O15344-1] ENST00000380780.5 [O15344-1] ENST00000675358.1 A0A8I5KPE0 C9J453 ENST00000380787.5 [O15344-1] ENST00000380779.5 [O15344-1] ENST00000616003.5 A0A8I5KPB2 O15344 A0A6Q8PGA5 A0A6Q8PGE7 |