MID1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0032874Biological processpositive regulation of stress-activated MAPK cascade
GO_0007026Biological processnegative regulation of microtubule depolymerization
GO_0035372Biological processprotein localization to microtubule
GO_0000226Biological processmicrotubule cytoskeleton organization
GO_0070507Biological processregulation of microtubule cytoskeleton organization
GO_0007389Biological processpattern specification process
GO_0034451Cellular componentcentriolar satellite
GO_0005874Cellular componentmicrotubule
GO_0005794Cellular componentGolgi apparatus
GO_0005829Cellular componentcytosol
GO_0005881Cellular componentcytoplasmic microtubule
GO_0005737Cellular componentcytoplasm
GO_0005875Cellular componentmicrotubule associated complex
GO_0005819Cellular componentspindle
GO_0019899Molecular functionenzyme binding
GO_0042803Molecular functionprotein homodimerization activity
GO_0016740Molecular functiontransferase activity
GO_0031625Molecular functionubiquitin protein ligase binding
GO_0042802Molecular functionidentical protein binding
GO_0008270Molecular functionzinc ion binding
GO_0008017Molecular functionmicrotubule binding
GO_0051219Molecular functionphosphoprotein binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameMID1
Protein nameMidline 1
E3 ubiquitin-protein ligase Midline-1 (EC 2.3.2.27) (RING finger protein Midline-1) (RING-type E3 ubiquitin transferase Midline-1) (Tripartite motif-containing protein 18)
E3 ubiquitin-protein ligase Midline-1 (EC 2.3.2.27) (Midin) (Putative transcription factor XPRF) (RING finger protein 59) (RING finger protein Midline-1) (RING-type E3 ubiquitin transferase Midline-1) (Tripartite motif-containing protein 18)
RING-type E3 ubiquitin transferase (EC 2.3.2.27)
SynonymsRNF59
XPRF
FXY
TRIM18
DescriptionFUNCTION: Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination. .

FUNCTION: Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination. .

FUNCTION: Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination. .

FUNCTION: Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination. .

FUNCTION: Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination. .

AccessionsA0A6Q8PF94
ENST00000413894.5
A0A087X255
ENST00000453318.6 [O15344-1]
ENST00000675073.1
ENST00000690004.1
ENST00000380782.6 [O15344-2]
ENST00000413894.6 [O15344-1]
A0A8I5KR14
ENST00000687008.1
ENST00000691943.1
ENST00000380785.5 [O15344-1]
ENST00000689773.1
ENST00000674917.1
ENST00000317552.9 [O15344-1]
ENST00000380780.5 [O15344-1]
ENST00000675358.1
A0A8I5KPE0
C9J453
ENST00000380787.5 [O15344-1]
ENST00000380779.5 [O15344-1]
ENST00000616003.5
A0A8I5KPB2
O15344
A0A6Q8PGA5
A0A6Q8PGE7