MACC1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0051781Biological processpositive regulation of cell division
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0005737Cellular componentcytoplasm
GO_0005739Cellular componentmitochondrion
GO_0005634Cellular componentnucleus
GO_0008083Molecular functiongrowth factor activity

IV. Literature review

[source]
Gene nameMACC1
Protein nameMetastasis-associated in colon cancer protein 1 (SH3 domain-containing protein 7a5)
Synonyms
DescriptionFUNCTION: Acts as a transcription activator for MET and as a key regulator of HGF-MET signaling. Promotes cell motility, proliferation and hepatocyte growth factor (HGF)-dependent scattering in vitro and tumor growth and metastasis in vivo. .

AccessionsQ6ZN28
ENST00000332878.8
ENST00000589011.1
ENST00000400331.10