Name | Number of supported studies | Average coverage | |
---|---|---|---|
microglial cell | 13 studies | 48% ± 19% | |
dendritic cell | 9 studies | 31% ± 14% | |
myeloid cell | 8 studies | 25% ± 8% | |
macrophage | 8 studies | 35% ± 13% | |
B cell | 5 studies | 23% ± 7% | |
endothelial cell | 5 studies | 26% ± 8% | |
plasma cell | 5 studies | 42% ± 15% | |
fibroblast | 5 studies | 20% ± 4% | |
glutamatergic neuron | 5 studies | 45% ± 17% | |
monocyte | 4 studies | 25% ± 7% | |
plasmacytoid dendritic cell | 4 studies | 21% ± 5% | |
epithelial cell | 3 studies | 39% ± 15% | |
alveolar macrophage | 3 studies | 25% ± 7% | |
goblet cell | 3 studies | 25% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 1727.44 | 1445 / 1445 | 100% | 10.19 | 183 / 183 |
intestine | 100% | 3399.00 | 966 / 966 | 99% | 7.67 | 522 / 527 |
stomach | 98% | 1271.97 | 353 / 359 | 96% | 8.55 | 275 / 286 |
ovary | 100% | 2483.56 | 180 / 180 | 94% | 10.11 | 405 / 430 |
prostate | 100% | 3408.40 | 245 / 245 | 94% | 6.29 | 472 / 502 |
pancreas | 100% | 1377.60 | 327 / 328 | 91% | 5.43 | 162 / 178 |
lung | 100% | 2062.03 | 576 / 578 | 91% | 5.83 | 1047 / 1155 |
bladder | 100% | 2602.38 | 21 / 21 | 87% | 4.70 | 436 / 504 |
breast | 100% | 2216.09 | 459 / 459 | 85% | 4.68 | 946 / 1118 |
uterus | 100% | 3009.46 | 170 / 170 | 83% | 4.52 | 383 / 459 |
skin | 100% | 2919.36 | 1809 / 1809 | 78% | 4.71 | 368 / 472 |
thymus | 99% | 1545.10 | 648 / 653 | 78% | 3.50 | 470 / 605 |
kidney | 84% | 882.66 | 75 / 89 | 77% | 5.16 | 696 / 901 |
brain | 72% | 843.54 | 1907 / 2642 | 62% | 2.46 | 435 / 705 |
adrenal gland | 95% | 769.14 | 245 / 258 | 29% | 1.11 | 66 / 230 |
adipose | 100% | 2441.55 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 18.03 | 29 / 29 |
spleen | 100% | 4682.12 | 241 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 98% | 1430.86 | 1303 / 1335 | 0% | 0 | 0 / 0 |
peripheral blood | 94% | 2813.58 | 873 / 929 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 87% | 4.97 | 39 / 45 |
heart | 78% | 682.63 | 670 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 70% | 2.48 | 56 / 80 |
liver | 19% | 101.26 | 44 / 226 | 11% | 0.50 | 45 / 406 |
muscle | 29% | 163.86 | 236 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0050732 | Biological process | negative regulation of peptidyl-tyrosine phosphorylation |
GO_0035556 | Biological process | intracellular signal transduction |
GO_0006468 | Biological process | protein phosphorylation |
GO_1902533 | Biological process | positive regulation of intracellular signal transduction |
GO_0050731 | Biological process | positive regulation of peptidyl-tyrosine phosphorylation |
GO_0045453 | Biological process | bone resorption |
GO_0090263 | Biological process | positive regulation of canonical Wnt signaling pathway |
GO_0036035 | Biological process | osteoclast development |
GO_0005829 | Cellular component | cytosol |
GO_0005739 | Cellular component | mitochondrion |
GO_0005525 | Molecular function | GTP binding |
GO_0004674 | Molecular function | protein serine/threonine kinase activity |
GO_0042802 | Molecular function | identical protein binding |
GO_0005515 | Molecular function | protein binding |
GO_0106310 | Molecular function | protein serine kinase activity |
GO_0046872 | Molecular function | metal ion binding |
GO_0005524 | Molecular function | ATP binding |
Gene name | LRRK1 |
Protein name | Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1) LRRK1 protein Leucine rich repeat kinase 1 |
Synonyms | KIAA1790 |
Description | FUNCTION: Plays a role in the negative regulation of bone mass, acting through the maturation of osteoclasts. . |
Accessions | E9PMK9 ENST00000525284.5 E9PK39 ENST00000534045.5 A6H8V9 Q9BS11 ENST00000531270.5 ENST00000532029.6 [Q38SD2-2] E9PLF8 ENST00000526457.3 Q38SD2 ENST00000388948.8 [Q38SD2-1] H0YEW1 |