LRCH1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1990869Biological processcellular response to chemokine
GO_0034260Biological processnegative regulation of GTPase activity
GO_2000405Biological processnegative regulation of T cell migration
GO_0005737Cellular componentcytoplasm
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameLRCH1
Protein nameLRCH1 protein
Leucine-rich repeat and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1) (Neuronal protein 81) (NP81)
Leucine rich repeats and calponin homology domain containing 1
SynonymsKIAA1016
CHDC1
DescriptionFUNCTION: Acts as a negative regulator of GTPase CDC42 by sequestering CDC42-guanine exchange factor DOCK8. Probably by preventing CDC42 activation, negatively regulates CD4(+) T-cell migration. .

AccessionsC9JWE0
Q8TAR8
ENST00000389797.8 [Q9Y2L9-3]
Q9Y2L9
ENST00000389798.7 [Q9Y2L9-1]
ENST00000311191.10 [Q9Y2L9-2]
ENST00000463929.5
ENST00000478412.1
C9J5B8