LINGO1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0005615Cellular componentextracellular space
GO_0005886Cellular componentplasma membrane
GO_0031012Cellular componentextracellular matrix
GO_0005154Molecular functionepidermal growth factor receptor binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameLINGO1
Protein nameLeucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 (Leucine-rich repeat and immunoglobulin domain-containing protein 1) (Leucine-rich repeat neuronal protein 1) (Leucine-rich repeat neuronal protein 6A)
Leucine rich repeat and Ig domain containing 1
SynonymsLRRN6A
LERN1
UNQ201/PRO227
DescriptionFUNCTION: Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors . Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination . Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development (By similarity). .

AccessionsENST00000561030.5 [Q96FE5-2]
ENST00000564472.5
H3BMN3
ENST00000570216.5
H3BN48
Q96FE5
H3BQ49
ENST00000559893.5
ENST00000557798.1
H0YMX3
H0YNK7
ENST00000566711.5
ENST00000562933.5
ENST00000561686.5
ENST00000355300.7 [Q96FE5-1]
H3BS32
H3BMW2
ENST00000567726.5
H3BM59