LHX4 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of LHX4 at tissue level.

III. Associated gene sets

GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0009887Biological processanimal organ morphogenesis
GO_0001890Biological processplacenta development
GO_0030182Biological processneuron differentiation
GO_0043066Biological processnegative regulation of apoptotic process
GO_0021526Biological processmedial motor column neuron differentiation
GO_0006915Biological processapoptotic process
GO_0008045Biological processmotor neuron axon guidance
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0000977Molecular functionRNA polymerase II transcription regulatory region sequence-specific DNA binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0043565Molecular functionsequence-specific DNA binding
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0008327Molecular functionmethyl-CpG binding
GO_0008270Molecular functionzinc ion binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameLHX4
Protein nameLIM homeobox 4 isoform 2
LIM homeobox 4
LIM/homeobox protein Lhx4 (LIM homeobox protein 4)
LIM homeobox protein 4
LIM homeobox 4 isoform 1
Synonyms
DescriptionFUNCTION: May play a critical role in the development of respiratory control mechanisms and in the normal growth and maturation of the lung. Binds preferentially to methylated DNA . .

AccessionsENST00000561113.1
A0A0S2Z5S9
Q5RLJ1
H0YKF4
Q969G2
Q5RLJ3
Q5RLJ2
ENST00000263726.4
A0A0S2Z5S4