Name | Number of supported studies | Average coverage | |
---|---|---|---|
mast cell | 11 studies | 32% ± 11% | |
keratinocyte | 3 studies | 75% ± 18% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
skin | 3 studies | 34% ± 14% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
skin | 75% | 675918.76 | 1349 / 1809 | 20% | 354.23 | 95 / 472 |
esophagus | 45% | 1222.30 | 653 / 1445 | 49% | 61.60 | 90 / 183 |
tonsil | 0% | 0 | 0 / 0 | 80% | 76.51 | 36 / 45 |
peripheral blood | 73% | 1565.96 | 681 / 929 | 0% | 0 | 0 / 0 |
uterus | 19% | 2154.57 | 32 / 170 | 44% | 217.21 | 204 / 459 |
lung | 26% | 242.74 | 153 / 578 | 31% | 9.16 | 360 / 1155 |
breast | 24% | 161.59 | 108 / 459 | 17% | 24.10 | 190 / 1118 |
bladder | 10% | 44.29 | 2 / 21 | 30% | 38.94 | 152 / 504 |
intestine | 23% | 164.78 | 222 / 966 | 8% | 0.36 | 44 / 527 |
adipose | 31% | 876.92 | 376 / 1204 | 0% | 0 | 0 / 0 |
thymus | 19% | 147.81 | 125 / 653 | 11% | 0.97 | 66 / 605 |
pancreas | 13% | 131.52 | 43 / 328 | 16% | 0.68 | 28 / 178 |
muscle | 27% | 336.55 | 220 / 803 | 0% | 0 | 0 / 0 |
heart | 27% | 176.30 | 231 / 861 | 0% | 0 | 0 / 0 |
blood vessel | 27% | 597.69 | 354 / 1335 | 0% | 0 | 0 / 0 |
stomach | 17% | 89.73 | 61 / 359 | 4% | 0.06 | 12 / 286 |
prostate | 14% | 76.77 | 34 / 245 | 7% | 0.13 | 34 / 502 |
spleen | 20% | 100.17 | 48 / 241 | 0% | 0 | 0 / 0 |
kidney | 11% | 55.91 | 10 / 89 | 7% | 0.13 | 64 / 901 |
liver | 15% | 131.77 | 33 / 226 | 3% | 0.26 | 14 / 406 |
lymph node | 0% | 0 | 0 / 0 | 17% | 0.50 | 5 / 29 |
ovary | 16% | 82.29 | 28 / 180 | 1% | 0.07 | 5 / 430 |
brain | 14% | 126.42 | 365 / 2642 | 2% | 0.07 | 15 / 705 |
adrenal gland | 10% | 68.83 | 27 / 258 | 3% | 0.08 | 7 / 230 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0018149 | Biological process | peptide cross-linking |
GO_0061436 | Biological process | establishment of skin barrier |
GO_0031424 | Biological process | keratinization |
GO_0042730 | Biological process | fibrinolysis |
GO_0045765 | Biological process | regulation of angiogenesis |
GO_0045109 | Biological process | intermediate filament organization |
GO_0050728 | Biological process | negative regulation of inflammatory response |
GO_0051290 | Biological process | protein heterotetramerization |
GO_0006979 | Biological process | response to oxidative stress |
GO_0001867 | Biological process | complement activation, lectin pathway |
GO_0005615 | Cellular component | extracellular space |
GO_0005856 | Cellular component | cytoskeleton |
GO_0005576 | Cellular component | extracellular region |
GO_0016020 | Cellular component | membrane |
GO_0070062 | Cellular component | extracellular exosome |
GO_0062023 | Cellular component | collagen-containing extracellular matrix |
GO_0001533 | Cellular component | cornified envelope |
GO_0072562 | Cellular component | blood microparticle |
GO_1904813 | Cellular component | ficolin-1-rich granule lumen |
GO_0005829 | Cellular component | cytosol |
GO_0045095 | Cellular component | keratin filament |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0038023 | Molecular function | signaling receptor activity |
GO_0030246 | Molecular function | carbohydrate binding |
GO_0030280 | Molecular function | structural constituent of skin epidermis |
GO_0046982 | Molecular function | protein heterodimerization activity |
GO_0005515 | Molecular function | protein binding |
Gene name | KRT1 |
Protein name | Keratin, type II cytoskeletal 1 (67 kDa cytokeratin) (Cytokeratin-1) (CK-1) (Hair alpha protein) (Keratin-1) (K1) (Type-II keratin Kb1) Keratin, type II cytoskeletal 1 (Cytokeratin-1) (Keratin-1) (Type-II keratin Kb1) |
Synonyms | KRTA |
Description | FUNCTION: May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK. . |
Accessions | H6VRG0 H6VRF8 H6VRG1 H6VRG3 H6VRG2 H6VRF9 ENST00000252244.3 P04264 |