ILKAP report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006470Biological processprotein dephosphorylation
GO_0005737Cellular componentcytoplasm
GO_0005515Molecular functionprotein binding
GO_0017018Molecular functionmyosin phosphatase activity
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameILKAP
Protein nameTruncated integrin-linked kinase-associated serine/threonine phosphatase 2C
ILK associated serine/threonine phosphatase (Integrin-linked kinase associated phosphatase)
Integrin-linked kinase-associated serine/threonine phosphatase 2C (ILKAP) (EC 3.1.3.16)
ILK associated serine/threonine phosphatase
SynonymsILKAP2
ILKAP3
DescriptionFUNCTION: Protein phosphatase that may play a role in regulation of cell cycle progression via dephosphorylation of its substrates whose appropriate phosphorylation states might be crucial for cell proliferation. Selectively associates with integrin linked kinase (ILK), to modulate cell adhesion and growth factor signaling. Inhibits the ILK-GSK3B signaling axis and may play an important role in inhibiting oncogenic transformation. .

AccessionsB8Y6Z5
B8Y6Z6
ENST00000612675.4
H7C2I8
F8SNU7
ENST00000254654.8
E9PC05
Q9H0C8
F8SNU6
ENST00000622223.4
ENST00000457149.1
ENST00000450411.1