HTR4 | OmnibusX

Name	Number of supported studies	Average coverage
GABAergic neuron	4 studies	33% ± 12%	Explore
glutamatergic neuron	3 studies	40% ± 12%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of HTR4 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
intestine	94%	306.94	910 / 966	6%	0.11	34 / 527
blood vessel	95%	113.77	1273 / 1335	0%	0	0 / 0
adrenal gland	76%	64.47	196 / 258	11%	0.30	26 / 230
heart	84%	129.82	723 / 861	0%	0	0 / 0
brain	57%	106.70	1502 / 2642	7%	0.13	46 / 705
uterus	22%	8.07	37 / 170	1%	0.01	3 / 459
skin	17%	5.27	308 / 1809	0%	0.01	1 / 472
adipose	17%	5.79	199 / 1204	0%	0	0 / 0
breast	15%	6.17	70 / 459	0%	0.00	1 / 1118
lung	10%	2.96	58 / 578	2%	0.03	19 / 1155
esophagus	10%	3.14	141 / 1445	2%	0.03	3 / 183
stomach	4%	0.88	13 / 359	8%	0.17	22 / 286
thymus	10%	3.31	66 / 653	0%	0.01	2 / 605
liver	7%	2.24	16 / 226	3%	0.06	13 / 406
ovary	9%	2.68	17 / 180	0%	0	0 / 430
bladder	5%	1.48	1 / 21	2%	0.03	9 / 504
prostate	5%	1.76	12 / 245	0%	0	0 / 502
spleen	2%	0.70	6 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	2%	0.04	1 / 45
muscle	1%	0.36	12 / 803	0%	0	0 / 0
peripheral blood	1%	0.19	6 / 929	0%	0	0 / 0
pancreas	1%	0.17	2 / 328	0%	0	0 / 178
kidney	0%	0	0 / 89	0%	0.01	4 / 901
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007188	Biological process	adenylate cyclase-modulating G protein-coupled receptor signaling pathway
GO_0030277	Biological process	maintenance of gastrointestinal epithelium
GO_0120056	Biological process	large intestinal transit
GO_0098664	Biological process	G protein-coupled serotonin receptor signaling pathway
GO_0032098	Biological process	regulation of appetite
GO_0007186	Biological process	G protein-coupled receptor signaling pathway
GO_0007268	Biological process	chemical synaptic transmission
GO_0007187	Biological process	G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO_0070254	Biological process	mucus secretion
GO_0005886	Cellular component	plasma membrane
GO_0016020	Cellular component	membrane
GO_0030425	Cellular component	dendrite
GO_0045202	Cellular component	synapse
GO_0005737	Cellular component	cytoplasm
GO_0005768	Cellular component	endosome
GO_0030594	Molecular function	neurotransmitter receptor activity
GO_0099589	Molecular function	serotonin receptor activity
GO_0004993	Molecular function	G protein-coupled serotonin receptor activity
GO_0005515	Molecular function	protein binding

Gene name	HTR4
Protein name	5-hydroxytryptamine receptor 4 5-hydroxytryptamine receptor 4 (5-HT-4) (5-HT4) (Serotonin receptor 4) 5-hydroxytryptamine receptor 4 (Serotonin receptor 4)
Synonyms
Description	FUNCTION: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. FUNCTION: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. . FUNCTION: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. .
Accessions	ENST00000522588.5 [Q13639-5] A0A2D3FAF9 Q13639 ENST00000521530.6 [Q13639-2] E5RK45 ENST00000520514.5 [Q13639-9] ENST00000520086.1 ENST00000521735.5 [Q13639-5] ENST00000524063.3 ENST00000360693.7 [Q13639-8] E5RHV8 ENST00000517929.5 [Q13639-3] ENST00000377888.8 [Q13639-1]

HTR4 report