HOXD8 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of HOXD8 at tissue level.

III. Associated gene sets

GO_0008595Biological processanterior/posterior axis specification, embryo
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0048705Biological processskeletal system morphogenesis
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0000977Molecular functionRNA polymerase II transcription regulatory region sequence-specific DNA binding
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific

IV. Literature review

[source]
Gene nameHOXD8
Protein nameHomeobox protein Hox-D8
Homeobox protein Hox-D8 (Homeobox protein Hox-4E) (Homeobox protein Hox-5.4)
SynonymsHOX4E
DescriptionFUNCTION: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

FUNCTION: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. .

FUNCTION: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. .

AccessionsENST00000450510.2 [P13378-2]
P13378
A0A0A0MTF4
ENST00000313173.6 [P13378-1]
A0A0A0MSX5
ENST00000544999.2
ENST00000429017.2