I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| connective tissue cell | 4 studies | 24% ± 7% | |
| fibroblast | 3 studies | 31% ± 2% | |
| pericyte | 3 studies | 19% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| connective tissue cell | 4 studies | 24% ± 7% | |
| fibroblast | 3 studies | 31% ± 2% | |
| pericyte | 3 studies | 19% ± 2% |
Insufficient scRNA-seq data for expression of HOXA5 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| kidney | 100% | 1525.58 | 89 / 89 | 97% | 30.08 | 873 / 901 |
| adrenal gland | 100% | 5341.98 | 258 / 258 | 95% | 55.78 | 218 / 230 |
| prostate | 100% | 759.53 | 244 / 245 | 90% | 12.37 | 453 / 502 |
| bladder | 100% | 992.62 | 21 / 21 | 89% | 18.99 | 447 / 504 |
| uterus | 100% | 1540.75 | 170 / 170 | 88% | 19.66 | 403 / 459 |
| esophagus | 97% | 700.35 | 1407 / 1445 | 90% | 11.80 | 165 / 183 |
| lung | 99% | 1640.17 | 575 / 578 | 86% | 10.43 | 999 / 1155 |
| intestine | 100% | 1316.03 | 966 / 966 | 82% | 15.26 | 434 / 527 |
| stomach | 85% | 880.09 | 305 / 359 | 81% | 13.47 | 233 / 286 |
| skin | 96% | 458.66 | 1738 / 1809 | 70% | 11.76 | 329 / 472 |
| breast | 100% | 1032.94 | 458 / 459 | 47% | 5.87 | 524 / 1118 |
| ureter | 0% | 0 | 0 / 0 | 100% | 10.36 | 1 / 1 |
| adipose | 98% | 833.11 | 1181 / 1204 | 0% | 0 | 0 / 0 |
| pancreas | 7% | 14.63 | 24 / 328 | 82% | 10.34 | 146 / 178 |
| muscle | 89% | 315.44 | 713 / 803 | 0% | 0 | 0 / 0 |
| spleen | 82% | 262.22 | 197 / 241 | 0% | 0 | 0 / 0 |
| ovary | 29% | 189.06 | 53 / 180 | 44% | 9.47 | 190 / 430 |
| blood vessel | 64% | 313.90 | 853 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 59% | 5.15 | 17 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 58% | 5.90 | 26 / 45 |
| brain | 6% | 82.72 | 167 / 2642 | 30% | 7.43 | 214 / 705 |
| thymus | 22% | 48.16 | 146 / 653 | 4% | 0.96 | 27 / 605 |
| liver | 0% | 0.77 | 1 / 226 | 16% | 1.43 | 63 / 406 |
| peripheral blood | 1% | 1.09 | 5 / 929 | 0% | 0 | 0 / 0 |
| heart | 0% | 0.97 | 4 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0048286 | Biological process | lung alveolus development |
| GO_0060535 | Biological process | trachea cartilage morphogenesis |
| GO_0033599 | Biological process | regulation of mammary gland epithelial cell proliferation |
| GO_0060435 | Biological process | bronchiole development |
| GO_0045647 | Biological process | negative regulation of erythrocyte differentiation |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0048704 | Biological process | embryonic skeletal system morphogenesis |
| GO_0010628 | Biological process | positive regulation of gene expression |
| GO_0060441 | Biological process | epithelial tube branching involved in lung morphogenesis |
| GO_0035264 | Biological process | multicellular organism growth |
| GO_0030878 | Biological process | thyroid gland development |
| GO_0060749 | Biological process | mammary gland alveolus development |
| GO_0016525 | Biological process | negative regulation of angiogenesis |
| GO_0003016 | Biological process | respiratory system process |
| GO_0060644 | Biological process | mammary gland epithelial cell differentiation |
| GO_0060764 | Biological process | cell-cell signaling involved in mammary gland development |
| GO_0009952 | Biological process | anterior/posterior pattern specification |
| GO_0060638 | Biological process | mesenchymal-epithelial cell signaling |
| GO_0045639 | Biological process | positive regulation of myeloid cell differentiation |
| GO_0060480 | Biological process | lung goblet cell differentiation |
| GO_0060574 | Biological process | intestinal epithelial cell maturation |
| GO_0060484 | Biological process | lung-associated mesenchyme development |
| GO_0043065 | Biological process | positive regulation of apoptotic process |
| GO_0016477 | Biological process | cell migration |
| GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
| GO_0000785 | Cellular component | chromatin |
| GO_0005634 | Cellular component | nucleus |
| GO_0003677 | Molecular function | DNA binding |
| GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
| GO_0003700 | Molecular function | DNA-binding transcription factor activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | HOXA5 |
| Protein name | Homeobox protein Hox-A5 Homeobox protein Hox-A5 (Homeobox protein Hox-1C) |
| Synonyms | HOX1C |
| Description | FUNCTION: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Also binds to its own promoter. Binds specifically to the motif 5'-CYYNATTA[TG]Y-3'. FUNCTION: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Also binds to its own promoter. Binds specifically to the motif 5'-CYYNATTA[TG]Y-3'. . |
| Accessions | P20719 ENST00000222726.4 Q6FG31 |
