Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 11 studies | 21% ± 4% | |
| epithelial cell | 6 studies | 36% ± 19% | |
| basal cell | 6 studies | 26% ± 7% | |
| CD4-positive, alpha-beta T cell | 5 studies | 23% ± 10% | |
| naive B cell | 4 studies | 17% ± 2% | |
| B cell | 4 studies | 20% ± 3% | |
| CD16-negative, CD56-bright natural killer cell, human | 4 studies | 18% ± 1% | |
| fibroblast | 4 studies | 22% ± 3% | |
| pericyte | 4 studies | 17% ± 2% | |
| natural killer cell | 4 studies | 22% ± 5% | |
| pancreatic A cell | 3 studies | 24% ± 3% | |
| hematopoietic precursor cell | 3 studies | 25% ± 10% | |
| ciliated cell | 3 studies | 32% ± 7% | |
| GABAergic neuron | 3 studies | 23% ± 7% | |
| glutamatergic neuron | 3 studies | 30% ± 8% | |
| CD8-positive, alpha-beta T cell | 3 studies | 24% ± 8% | |
| dendritic cell | 3 studies | 35% ± 14% | |
| transit amplifying cell | 3 studies | 23% ± 7% | |
| erythroblast | 3 studies | 30% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| ovary | 100% | 2354.42 | 180 / 180 | 100% | 29.44 | 430 / 430 |
| stomach | 100% | 1952.35 | 359 / 359 | 100% | 35.05 | 286 / 286 |
| esophagus | 100% | 2396.65 | 1444 / 1445 | 100% | 40.48 | 183 / 183 |
| breast | 100% | 3021.89 | 459 / 459 | 100% | 46.05 | 1117 / 1118 |
| lung | 100% | 2539.11 | 577 / 578 | 100% | 37.18 | 1155 / 1155 |
| intestine | 100% | 2249.58 | 966 / 966 | 100% | 38.01 | 526 / 527 |
| bladder | 100% | 2672.57 | 21 / 21 | 100% | 41.71 | 502 / 504 |
| uterus | 100% | 2515.53 | 170 / 170 | 100% | 40.71 | 457 / 459 |
| prostate | 100% | 2130.32 | 245 / 245 | 99% | 25.43 | 498 / 502 |
| brain | 99% | 1505.44 | 2618 / 2642 | 100% | 24.56 | 705 / 705 |
| thymus | 100% | 2138.00 | 653 / 653 | 99% | 21.42 | 597 / 605 |
| pancreas | 100% | 1381.52 | 327 / 328 | 99% | 26.82 | 176 / 178 |
| skin | 100% | 3618.09 | 1809 / 1809 | 98% | 35.78 | 463 / 472 |
| liver | 100% | 1337.77 | 226 / 226 | 97% | 18.42 | 394 / 406 |
| kidney | 100% | 1645.19 | 89 / 89 | 95% | 16.94 | 857 / 901 |
| adrenal gland | 100% | 4592.93 | 258 / 258 | 94% | 23.28 | 217 / 230 |
| adipose | 100% | 3284.04 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 52.18 | 29 / 29 |
| muscle | 100% | 3739.34 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 2617.63 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 31.17 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 21.64 | 1 / 1 |
| blood vessel | 100% | 2217.16 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| heart | 97% | 1769.00 | 832 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 94% | 20.36 | 75 / 80 |
| peripheral blood | 69% | 2256.68 | 638 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0008285 | Biological process | negative regulation of cell population proliferation |
| GO_0033342 | Biological process | negative regulation of collagen binding |
| GO_0001649 | Biological process | osteoblast differentiation |
| GO_0000079 | Biological process | regulation of cyclin-dependent protein serine/threonine kinase activity |
| GO_0042273 | Biological process | ribosomal large subunit biogenesis |
| GO_0031397 | Biological process | negative regulation of protein ubiquitination |
| GO_0008156 | Biological process | negative regulation of DNA replication |
| GO_0050821 | Biological process | protein stabilization |
| GO_0000463 | Biological process | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| GO_0030336 | Biological process | negative regulation of cell migration |
| GO_0022408 | Biological process | negative regulation of cell-cell adhesion |
| GO_0005730 | Cellular component | nucleolus |
| GO_0048471 | Cellular component | perinuclear region of cytoplasm |
| GO_0016020 | Cellular component | membrane |
| GO_0005634 | Cellular component | nucleus |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0031965 | Cellular component | nuclear membrane |
| GO_1990275 | Molecular function | preribosome binding |
| GO_0005525 | Molecular function | GTP binding |
| GO_0003723 | Molecular function | RNA binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0003924 | Molecular function | GTPase activity |
| Gene name | GTPBP4 |
| Protein name | Nucleolar GTP-binding protein 1 GTP binding protein 4 GTPBP4 protein GTP-binding protein 4 (Chronic renal failure gene protein) (GTP-binding protein NGB) (Nucleolar GTP-binding protein 1) |
| Synonyms | CRFG NOG1 |
| Description | FUNCTION: Involved in the biogenesis of the 60S ribosomal subunit . Acts as a TP53 repressor, preventing TP53 stabilization and cell cycle arrest . . FUNCTION: Involved in the biogenesis of the 60S ribosomal subunit. . |
| Accessions | Q8N4P8 Q5T3R7 ENST00000360803.9 [Q9BZE4-1] Q9BZE4 D2CFK9 ENST00000360059.5 |