GTPBP4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0008285Biological processnegative regulation of cell population proliferation
GO_0033342Biological processnegative regulation of collagen binding
GO_0001649Biological processosteoblast differentiation
GO_0000079Biological processregulation of cyclin-dependent protein serine/threonine kinase activity
GO_0042273Biological processribosomal large subunit biogenesis
GO_0031397Biological processnegative regulation of protein ubiquitination
GO_0008156Biological processnegative regulation of DNA replication
GO_0050821Biological processprotein stabilization
GO_0000463Biological processmaturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO_0030336Biological processnegative regulation of cell migration
GO_0022408Biological processnegative regulation of cell-cell adhesion
GO_0005730Cellular componentnucleolus
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0016020Cellular componentmembrane
GO_0005634Cellular componentnucleus
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0031965Cellular componentnuclear membrane
GO_1990275Molecular functionpreribosome binding
GO_0005525Molecular functionGTP binding
GO_0003723Molecular functionRNA binding
GO_0005515Molecular functionprotein binding
GO_0003924Molecular functionGTPase activity

IV. Literature review

[source]
Gene nameGTPBP4
Protein nameNucleolar GTP-binding protein 1
GTP binding protein 4
GTPBP4 protein
GTP-binding protein 4 (Chronic renal failure gene protein) (GTP-binding protein NGB) (Nucleolar GTP-binding protein 1)
SynonymsCRFG
NOG1
DescriptionFUNCTION: Involved in the biogenesis of the 60S ribosomal subunit . Acts as a TP53 repressor, preventing TP53 stabilization and cell cycle arrest . .

FUNCTION: Involved in the biogenesis of the 60S ribosomal subunit. .

AccessionsQ8N4P8
Q5T3R7
ENST00000360803.9 [Q9BZE4-1]
Q9BZE4
D2CFK9
ENST00000360059.5