GRPEL1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006457Biological processprotein folding
GO_0030150Biological processprotein import into mitochondrial matrix
GO_0006886Biological processintracellular protein transport
GO_0001405Cellular componentPAM complex, Tim23 associated import motor
GO_0005744Cellular componentTIM23 mitochondrial import inner membrane translocase complex
GO_0005654Cellular componentnucleoplasm
GO_0005759Cellular componentmitochondrial matrix
GO_0005743Cellular componentmitochondrial inner membrane
GO_0005739Cellular componentmitochondrion
GO_0042803Molecular functionprotein homodimerization activity
GO_0051082Molecular functionunfolded protein binding
GO_0051087Molecular functionprotein-folding chaperone binding
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding
GO_0000774Molecular functionadenyl-nucleotide exchange factor activity

IV. Literature review

[source]
Gene nameGRPEL1
Protein nameGrpE protein homolog 1, mitochondrial (HMGE) (Mt-GrpE#1)
GrpE like 1, mitochondrial
SynonymsGREPEL1
DescriptionFUNCTION: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner (By similarity). Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins . .

AccessionsENST00000264954.5
ENST00000706688.1
A0A9L9PX72
A0A9L9PY91
Q9HAV7
ENST00000706689.1