GNPTG report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0046835Biological processcarbohydrate phosphorylation
GO_0016256Biological processN-glycan processing to lysosome
GO_0000139Cellular componentGolgi membrane
GO_0070062Cellular componentextracellular exosome
GO_0005794Cellular componentGolgi apparatus
GO_0070622Cellular componentUDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complex
GO_0042803Molecular functionprotein homodimerization activity
GO_0005515Molecular functionprotein binding
GO_0003976Molecular functionUDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity

IV. Literature review

[source]
Gene nameGNPTG
Protein nameN-acetylglucosamine-1-phosphate transferase, gamma subunit, isoform CRA_b (Similar to protein kinase C substrate)
N-acetylglucosamine-1-phosphate transferase subunit gamma
N-acetylglucosamine-1-phosphotransferase subunit gamma (GlcNAc-1-phosphotransferase subunit gamma) (UDP-N-acetylglucosamine-1-phosphotransferase subunit gamma)
GNPTG protein
SynonymsCAB56184
GNPTAG
hCG_42715
LP2537
RJD9
C16orf27
DescriptionFUNCTION: Non-catalytic subunit of the N-acetylglucosamine-1-phosphotransferase complex, an enzyme that catalyzes the formation of mannose 6-phosphate (M6P) markers on high mannose type oligosaccharides in the Golgi apparatus. Binds and presents the high mannose glycans of the acceptor to the catalytic alpha and beta subunits (GNPTAB). Enhances the rate of N-acetylglucosamine-1-phosphate transfer to the oligosaccharides of acid hydrolase acceptors. .

AccessionsENST00000683366.1
A0A804HIZ1
ENST00000526820.5
H0YEA7
Q96RZ2
ENST00000529110.2
ENST00000527137.2
ENST00000683887.1
A0A087WWA2
A0A804HI41
Q9UJJ9
A2VDJ4
E9PQQ5
ENST00000204679.9