GNG7 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0001662Biological processbehavioral fear response
GO_0007168Biological processreceptor guanylyl cyclase signaling pathway
GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0008277Biological processregulation of G protein-coupled receptor signaling pathway
GO_0007626Biological processlocomotory behavior
GO_0005834Cellular componentheterotrimeric G-protein complex
GO_0070062Cellular componentextracellular exosome
GO_0005886Cellular componentplasma membrane
GO_0031681Molecular functionG-protein beta-subunit binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameGNG7
Protein nameGuanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
G protein subunit gamma 7
SynonymsGNGT7
DescriptionFUNCTION: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilzation of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striatum (By similarity). .

AccessionsENST00000382159.8
K7ESC6
ENST00000587867.1
O60262