Name | Number of supported studies | Average coverage | |
---|---|---|---|
B cell | 35 studies | 28% ± 9% | |
naive B cell | 17 studies | 28% ± 7% | |
memory B cell | 16 studies | 28% ± 7% | |
macrophage | 14 studies | 26% ± 10% | |
plasmacytoid dendritic cell | 12 studies | 31% ± 12% | |
microglial cell | 9 studies | 32% ± 10% | |
endothelial cell | 8 studies | 29% ± 13% | |
glutamatergic neuron | 8 studies | 38% ± 25% | |
retinal rod cell | 7 studies | 36% ± 16% | |
myeloid cell | 6 studies | 25% ± 7% | |
retinal cone cell | 6 studies | 34% ± 11% | |
type I pneumocyte | 6 studies | 23% ± 6% | |
astrocyte | 6 studies | 26% ± 7% | |
epithelial cell | 5 studies | 38% ± 11% | |
GABAergic neuron | 5 studies | 51% ± 19% | |
alveolar macrophage | 5 studies | 34% ± 14% | |
leukocyte | 4 studies | 26% ± 3% | |
natural killer cell | 4 studies | 17% ± 1% | |
retinal bipolar neuron | 4 studies | 24% ± 5% | |
immature B cell | 4 studies | 29% ± 9% | |
retinal pigment epithelial cell | 4 studies | 41% ± 14% | |
germinal center B cell | 4 studies | 41% ± 16% | |
oligodendrocyte precursor cell | 4 studies | 28% ± 10% | |
interneuron | 4 studies | 48% ± 23% | |
GABAergic interneuron | 3 studies | 21% ± 2% | |
precursor B cell | 3 studies | 27% ± 7% | |
amacrine cell | 3 studies | 23% ± 4% | |
ciliated cell | 3 studies | 28% ± 2% | |
lymphocyte | 3 studies | 24% ± 7% | |
effector memory CD8-positive, alpha-beta T cell | 3 studies | 24% ± 6% | |
type II pneumocyte | 3 studies | 23% ± 5% | |
dendritic cell | 3 studies | 35% ± 12% | |
granulocyte monocyte progenitor cell | 3 studies | 23% ± 10% | |
monocyte | 3 studies | 28% ± 11% | |
basal cell | 3 studies | 40% ± 22% | |
abnormal cell | 3 studies | 30% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 4979.37 | 1445 / 1445 | 100% | 27.26 | 183 / 183 |
pancreas | 100% | 9535.41 | 328 / 328 | 100% | 34.19 | 178 / 178 |
thymus | 100% | 14076.65 | 653 / 653 | 100% | 88.59 | 605 / 605 |
uterus | 100% | 6936.88 | 170 / 170 | 100% | 39.62 | 459 / 459 |
skin | 100% | 5114.73 | 1808 / 1809 | 100% | 54.36 | 472 / 472 |
breast | 100% | 6338.11 | 459 / 459 | 100% | 57.36 | 1117 / 1118 |
lung | 100% | 10422.12 | 578 / 578 | 100% | 43.07 | 1153 / 1155 |
bladder | 100% | 5771.05 | 21 / 21 | 100% | 32.56 | 503 / 504 |
prostate | 100% | 10710.37 | 245 / 245 | 100% | 37.97 | 501 / 502 |
adrenal gland | 100% | 11536.78 | 258 / 258 | 100% | 45.01 | 229 / 230 |
kidney | 100% | 7473.76 | 89 / 89 | 100% | 45.71 | 897 / 901 |
intestine | 100% | 6623.27 | 966 / 966 | 99% | 28.94 | 523 / 527 |
ovary | 100% | 11573.22 | 180 / 180 | 99% | 24.25 | 426 / 430 |
stomach | 100% | 6260.72 | 359 / 359 | 99% | 27.18 | 282 / 286 |
liver | 100% | 3002.10 | 226 / 226 | 96% | 21.84 | 388 / 406 |
brain | 94% | 4650.99 | 2495 / 2642 | 100% | 24.39 | 704 / 705 |
adipose | 100% | 5185.28 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 51.77 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 132.99 | 29 / 29 |
spleen | 100% | 15140.59 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 65.63 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 11.73 | 1 / 1 |
muscle | 100% | 4631.18 | 802 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 4082.78 | 1329 / 1335 | 0% | 0 | 0 / 0 |
heart | 97% | 3874.42 | 836 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 89% | 6046.62 | 826 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006886 | Biological process | intracellular protein transport |
GO_0043001 | Biological process | Golgi to plasma membrane protein transport |
GO_0034394 | Biological process | protein localization to cell surface |
GO_0006893 | Biological process | Golgi to plasma membrane transport |
GO_0005802 | Cellular component | trans-Golgi network |
GO_0010008 | Cellular component | endosome membrane |
GO_0031901 | Cellular component | early endosome membrane |
GO_0030136 | Cellular component | clathrin-coated vesicle |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0043130 | Molecular function | ubiquitin binding |
GO_0005515 | Molecular function | protein binding |
GO_0031267 | Molecular function | small GTPase binding |
GO_0035091 | Molecular function | phosphatidylinositol binding |
Gene name | GGA2 |
Protein name | ADP-ribosylation factor-binding protein GGA2 (Gamma-adaptin-related protein 2) (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear) Golgi associated, gamma adaptin ear containing, ARF binding protein 2 |
Synonyms | KIAA1080 |
Description | FUNCTION: Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (DXXLL) motif . Mediates export of the GPCR receptor ADRA2B to the cell surface . Regulates retrograde transport of phosphorylated form of BACE1 from endosomes to the trans-Golgi network . . |
Accessions | H3BMM6 H3BPF4 I3L263 I3L2C4 Q9UJY4 ENST00000570111.5 H3BPI3 H3BMN6 ENST00000563047.1 ENST00000562944.5 ENST00000569300.5 ENST00000562117.1 ENST00000567468.5 ENST00000563494.5 ENST00000569189.2 ENST00000309859.8 |