Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 11 studies | 27% ± 10% | |
microglial cell | 10 studies | 34% ± 11% | |
macrophage | 10 studies | 27% ± 10% | |
B cell | 7 studies | 19% ± 3% | |
epithelial cell | 7 studies | 35% ± 14% | |
natural killer cell | 6 studies | 20% ± 4% | |
ciliated cell | 6 studies | 23% ± 7% | |
classical monocyte | 6 studies | 25% ± 10% | |
endothelial cell of lymphatic vessel | 5 studies | 28% ± 14% | |
CD16-positive, CD56-dim natural killer cell, human | 5 studies | 18% ± 3% | |
glutamatergic neuron | 5 studies | 34% ± 21% | |
myeloid cell | 5 studies | 25% ± 3% | |
astrocyte | 5 studies | 27% ± 10% | |
monocyte | 5 studies | 21% ± 5% | |
goblet cell | 5 studies | 31% ± 16% | |
respiratory goblet cell | 4 studies | 23% ± 5% | |
squamous epithelial cell | 4 studies | 40% ± 18% | |
non-classical monocyte | 4 studies | 27% ± 11% | |
lymphocyte | 4 studies | 25% ± 6% | |
basal cell | 4 studies | 27% ± 13% | |
fibroblast | 4 studies | 19% ± 4% | |
plasmacytoid dendritic cell | 4 studies | 23% ± 7% | |
secretory cell | 3 studies | 19% ± 2% | |
CD16-negative, CD56-bright natural killer cell, human | 3 studies | 18% ± 3% | |
CD8-positive, alpha-beta T cell | 3 studies | 20% ± 3% | |
hematopoietic precursor cell | 3 studies | 20% ± 2% | |
neuron | 3 studies | 22% ± 8% | |
GABAergic neuron | 3 studies | 36% ± 15% | |
dendritic cell | 3 studies | 32% ± 12% | |
club cell | 3 studies | 18% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 7270.19 | 1445 / 1445 | 100% | 29.89 | 183 / 183 |
intestine | 100% | 9374.55 | 966 / 966 | 100% | 32.16 | 527 / 527 |
ovary | 100% | 7630.19 | 180 / 180 | 100% | 20.07 | 430 / 430 |
pancreas | 100% | 5416.50 | 328 / 328 | 100% | 30.66 | 178 / 178 |
prostate | 100% | 8937.89 | 245 / 245 | 100% | 26.46 | 502 / 502 |
stomach | 100% | 7965.72 | 359 / 359 | 100% | 30.39 | 286 / 286 |
thymus | 100% | 8328.88 | 653 / 653 | 100% | 25.04 | 605 / 605 |
breast | 100% | 7042.81 | 459 / 459 | 100% | 24.87 | 1116 / 1118 |
bladder | 100% | 7440.00 | 21 / 21 | 100% | 25.80 | 503 / 504 |
uterus | 100% | 9578.91 | 170 / 170 | 100% | 22.65 | 458 / 459 |
adrenal gland | 100% | 7329.37 | 258 / 258 | 100% | 19.09 | 229 / 230 |
kidney | 100% | 9078.20 | 89 / 89 | 100% | 19.76 | 897 / 901 |
skin | 100% | 6664.90 | 1809 / 1809 | 99% | 23.84 | 469 / 472 |
lung | 100% | 9476.96 | 578 / 578 | 99% | 22.90 | 1147 / 1155 |
liver | 100% | 4810.33 | 226 / 226 | 99% | 15.56 | 403 / 406 |
brain | 99% | 5751.26 | 2628 / 2642 | 100% | 20.60 | 702 / 705 |
adipose | 100% | 6281.90 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 27.04 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 29.17 | 29 / 29 |
spleen | 100% | 12155.36 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 22.45 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 18.39 | 1 / 1 |
blood vessel | 100% | 6076.11 | 1334 / 1335 | 0% | 0 | 0 / 0 |
peripheral blood | 99% | 6907.03 | 917 / 929 | 0% | 0 | 0 / 0 |
heart | 98% | 3027.04 | 847 / 861 | 0% | 0 | 0 / 0 |
muscle | 98% | 3395.33 | 788 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0046907 | Biological process | intracellular transport |
GO_0072659 | Biological process | protein localization to plasma membrane |
GO_0016191 | Biological process | synaptic vesicle uncoating |
GO_0006898 | Biological process | receptor-mediated endocytosis |
GO_1905443 | Biological process | regulation of clathrin coat assembly |
GO_0007029 | Biological process | endoplasmic reticulum organization |
GO_0072318 | Biological process | clathrin coat disassembly |
GO_0034067 | Biological process | protein localization to Golgi apparatus |
GO_0007030 | Biological process | Golgi organization |
GO_0048268 | Biological process | clathrin coat assembly |
GO_0010977 | Biological process | negative regulation of neuron projection development |
GO_0090160 | Biological process | Golgi to lysosome transport |
GO_0072583 | Biological process | clathrin-dependent endocytosis |
GO_0051085 | Biological process | chaperone cofactor-dependent protein refolding |
GO_0098793 | Cellular component | presynapse |
GO_0048471 | Cellular component | perinuclear region of cytoplasm |
GO_0016020 | Cellular component | membrane |
GO_0030136 | Cellular component | clathrin-coated vesicle |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0005925 | Cellular component | focal adhesion |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0031982 | Cellular component | vesicle |
GO_0106310 | Molecular function | protein serine kinase activity |
GO_0004674 | Molecular function | protein serine/threonine kinase activity |
GO_0051087 | Molecular function | protein-folding chaperone binding |
GO_0005524 | Molecular function | ATP binding |
GO_0030276 | Molecular function | clathrin binding |
GO_0005515 | Molecular function | protein binding |
GO_0030332 | Molecular function | cyclin binding |
Gene name | GAK |
Protein name | Cyclin-G-associated kinase (EC 2.7.11.1) Cyclin G associated kinase GAK protein |
Synonyms | hCG_1982003 |
Description | FUNCTION: Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1 . May play a role in clathrin-mediated endocytosis and intracellular trafficking, and in the dynamics of clathrin assembly/disassembly . . |
Accessions | ENST00000502656.5 ENST00000510799.1 D6RC24 D6RF16 ENST00000507580.5 H0Y8H5 ENST00000511229.5 ENST00000511163.5 [O14976-2] ENST00000628912.1 D6RAW3 ENST00000511980.5 ENST00000314167.9 [O14976-1] O14976 H0Y9M4 ENST00000505819.5 ENST00000512325.3 H0YA39 ENST00000504668.5 D6RAQ7 Q3B835 D6RE78 |