GABRQ report

I. Expression across cell types

Insufficient scRNA-seq data for expression of GABRQ at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of GABRQ at tissue level.

III. Associated gene sets

GO_0042391Biological processregulation of membrane potential
GO_0007165Biological processsignal transduction
GO_1902476Biological processchloride transmembrane transport
GO_0007268Biological processchemical synaptic transmission
GO_0006836Biological processneurotransmitter transport
GO_0043235Cellular componentreceptor complex
GO_0005886Cellular componentplasma membrane
GO_1902495Cellular componenttransmembrane transporter complex
GO_0043005Cellular componentneuron projection
GO_0034707Cellular componentchloride channel complex
GO_0045202Cellular componentsynapse
GO_0045211Cellular componentpostsynaptic membrane
GO_1902711Cellular componentGABA-A receptor complex
GO_0004890Molecular functionGABA-A receptor activity
GO_0004888Molecular functiontransmembrane signaling receptor activity
GO_0005326Molecular functionneurotransmitter transmembrane transporter activity
GO_0030594Molecular functionneurotransmitter receptor activity
GO_0022851Molecular functionGABA-gated chloride ion channel activity
GO_0005515Molecular functionprotein binding
GO_0005254Molecular functionchloride channel activity

IV. Literature review

[source]
Gene nameGABRQ
Protein nameGamma-aminobutyric acid receptor subunit theta (GABA(A) receptor subunit theta)
Synonyms
DescriptionFUNCTION: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.

AccessionsQ9UN88
ENST00000598523.3