FLYWCH1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006974Biological processDNA damage response
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0016604Cellular componentnuclear body
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005721Cellular componentpericentric heterochromatin
GO_0005667Cellular componenttranscription regulator complex
GO_0003677Molecular functionDNA binding
GO_0001223Molecular functiontranscription coactivator binding
GO_0003714Molecular functiontranscription corepressor activity
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameFLYWCH1
Protein nameFLYWCH-type zinc finger 1
FLYWCH-type zinc finger-containing protein 1
SynonymsKIAA1552
DescriptionFUNCTION: Transcription cofactor . Negatively regulates transcription activation by catenin beta-1 CTNNB1, perhaps acting by competing with TCF4 for CTNNB1 binding . May play a role in DNA-damage response signaling . Binds specifically to DNA sequences at peri-centromeric chromatin loci. .

AccessionsENST00000571983.5
ENST00000573564.5
I3L231
ENST00000570425.5
ENST00000571580.1
J3KNW1
I3L0R3
ENST00000416288.6 [Q4VC44-2]
ENST00000344592.9
I3L1A7
I3L4V9
I3L188
I3L287
ENST00000575679.1
ENST00000253928.14 [Q4VC44-1]
ENST00000573525.1
Q4VC44